Special

MmuEX0038885 @ mm10

Exon Skipping

Gene
Description
RAS p21 protein activator 4 [Source:MGI Symbol;Acc:MGI:1858600]
Coordinates
chr5:136101625-136102427:+
Coord C1 exon
chr5:136101625-136101689
Coord A exon
chr5:136101945-136102057
Coord C2 exon
chr5:136102235-136102427
Length
113 bp
Sequences
Splice sites
3' ss Seq
TGGTTTATGGTGGCTCTCAGGTG
3' ss Score
7.12
5' ss Seq
AGGGTGAGG
5' ss Score
7.13
Exon sequences
Seq C1 exon
GTGAAGCCAACACCCTCTTCCGGAGCAATTCTCTGGCCTCAAAGTCCATGGAGTCTTTCCTGAAG
Seq A exon
GTGGCAGGGATGCGCTATCTGCATGGCATCCTGGGCCCCATCATTGACAGAGTGTTCGAGGAGAAGAAGTACGTGGAGCTGGACCCCAGCAAAGTGGAAGTTAAGGATGTAGG
Seq C2 exon
GTGCTCTGGGCTGCACCGCCCACAGACCGAAGCTGAAGTGTTAGAGCAGAGTGCACAGACGCTGCGTGCCCACTTAGTGGCGCTGCTGAGCGCCATATGCCGCTCGGTTCGCACGTGCCCAGCCATCATCCGCGCCACATTCCGGCAGCTGTTCAGGCGCGTGCGCGAGCGCTTCCCGAACGCCCAGCACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000004952_MULTIEX2-4/4=3-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.009 C2=0.015
Domain overlap (PFAM):

C1:
PF0061614=RasGAP=FE(11.1=100)
A:
PF0061614=RasGAP=FE(19.5=100)
C2:
PF0061614=RasGAP=FE(33.7=100)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
([1])
Chicken
(galGal3)
HIGH PSI
([2])
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCCTCTTCCGGAGCAATTC
R:
TGCTGGGCGTTCGGGAAG
Band lengths:
244-357
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types