MmuEX0041260 @ mm10
Exon Skipping
Gene
ENSMUSG00000075318 | Scn2a
Description
sodium channel, voltage-gated, type II, alpha [Source:MGI Symbol;Acc:MGI:98248]
Coordinates
chr2:65707228-65711945:+
Coord C1 exon
chr2:65707228-65707360
Coord A exon
chr2:65708918-65709052
Coord C2 exon
chr2:65711707-65711945
Length
135 bp
Sequences
Splice sites
3' ss Seq
GCTCCTCCCTATCCCTCCAGGTA
3' ss Score
11.58
5' ss Seq
AGGGTAAGT
5' ss Score
10.45
Exon sequences
Seq C1 exon
GGCACAACTACTGAAACAGAAATAAGGAAGAGGAGGTCCAGTTCTTACCATGTTTCTATGGACTTGTTGGAAGACCCTACATCAAGGCAAAGAGCAATGAGTATGGCCAGCATTTTGACCAACACTATGGAAG
Seq A exon
GTAAATCTTTTGAAGAGTCTCTGGTCTTCGGCTCCTTGCCATAGCAAAACCACTGAGAGGAAGGGGCCAGTGGTTCTGCTTCCGATGTCAGCAGCATGGCTGCTCCCCAAAGCAGGAAGTAGAGAAGGAGCCAGG
Seq C2 exon
AACTTGAAGAATCCAGACAGAAATGCCCTCCATGCTGGTATAAATTTGCTAATATGTGCCTGATTTGGGACTGTTGTAAGCCATGGCTAAAGGTAAAACATGTTGTCAATCTGGTAGTGATGGATCCATTCGTTGACCTGGCCATCACCATCTGCATTGTGTTAAATACACTCTTCATGGCCATGGAGCACTACCCGATGACGGAGCAGTTCAGCAGTGTGCTGTCTGTTGGGAATTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075318_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.449 A=0.071 C2=0.000
Domain overlap (PFAM):
C1:
PF119333=DUF3451=PD(16.5=82.2)
A:
NO
C2:
PF0052026=Ion_trans=PU(1.6=3.8)
Main Inclusion Isoform:
ENSMUST00000028377fB3596
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCCAGCATTTTGACCAACAC
R:
CTGCTGAACTGCTCCGTCATC
Band lengths:
246-381
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types