Special

MmuEX0046419 @ mm10

Exon Skipping

Gene
ENSMUSG00000029192 | Tbc1d14
Description
TBC1 domain family, member 14 [Source:MGI Symbol;Acc:MGI:1098708]
Coordinates
chr5:36495018-36508431:-
Coord C1 exon
chr5:36508360-36508431
Coord A exon
chr5:36507578-36507706
Coord C2 exon
chr5:36495018-36495276
Length
129 bp
Sequences
Splice sites
3' ss Seq
ACCTTTCTCTCCTTCCTCAGGTT
3' ss Score
12.88
5' ss Seq
CTTGTGAGT
5' ss Score
7.15
Exon sequences
Seq C1 exon
GGTGGTCCGTATCATGACATGTTGCACAGTATTTTGGGCGCTTATACTTGTTACCGGCCGGATGTGGGTTAT
Seq A exon
GTTCAGGGCATGTCCTTTATAGCTGCAGTGTTGATCTTGAACCTCGATACTGCAGATGCCTTTATTGCTTTTTCTAATCTTTTGAATAAACCCTGTCAAATGGCGTTTTTCCGAGTGGACCATGGCCTT
Seq C2 exon
GATTTTCACCTTGTACAGTAAGTCCCTGCCCTTGGACTTGGCCTGCCGCATCTGGGACGTATTCTGTCGAGATGGAGAGGAATTTCTCTTCCGCACAGCTCTGGGCATCCTGAAGCTTTTTGAAGATATCCTGACCAGGATGGACTTCATCCACAGTGCCCAGTTTCTGACCAGGCTGCCTGAGGACCTGCCCGCAGATGAAGTGTTTGCAGCTATCTCCACAGTCCAGATGCAAAGCCGGAACAAGAAATGGGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000029192_MULTIEX1-12/14=10-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0056613=RabGAP-TBC=FE(10.1=100)

							
A:
PF0056613=RabGAP-TBC=FE(18.4=100)

							
C2:
PF0056613=RabGAP-TBC=PD(19.7=51.7)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000134405





     
                   









    
Main Skipping Isoform:
ENSMUST00000124036fB4048





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000031094, ENSMUSP00000114508, ENSMUSP00000115926, ENSMUSP00000116519, ENSMUSP00000117414, ENSMUSP00000121516, ENSMUSP00000121816, ENSMUSP00000131876
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr4:7010653-7010781 
HIGH PSI
HsaEX6083491
(TBC1D14)
Human
(hg19)
chr4:7012380-7012508 
HIGH PSI
HsaEX6083491
(TBC1D14)
Rat
(rn6)
chr14:79426412-79426540 
HIGH PSI
RnoEX0088807
(Tbc1d14)
Cow
(bosTau6)
chr6:118289618-118289746 
HIGH PSI
BtaEX0035698
(TBC1D14)
Chicken
(galGal4)
chr4:79491260-79491388 
HIGH PSI
GgaEX1057316
(TBC1D14)
Chicken
(galGal3)
chr4:82884549-82884677 
HIGH PSI
GgaEX1057316
(TBC1D14)
Zebrafish
(danRer10)
chr7:39427450-39427578 
HIGH PSI
DreEX0077405
(tbc1d14)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TACTTGTTACCGGCCGGATGT

				
R: 
TGGACTGTGGAGATAGCTGCA

				
Band lengths: 
256-385

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"