Special

MmuEX0047475 @ mm9

Exon Skipping

Gene
ENSMUSG00000020694 | Tlk2
Description
tousled-like kinase 2 (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1346023]
Coordinates
chr11:105082500-105108198:+
Coord C1 exon
chr11:105082500-105082667
Coord A exon
chr11:105102883-105102975
Coord C2 exon
chr11:105108088-105108198
Length
93 bp
Sequences
Splice sites
3' ss Seq
GTTTGCTTTTGTCTTTGTAGTCT
3' ss Score
8.75
5' ss Seq
AGAGTAAGT
5' ss Score
9.35
Exon sequences
Seq C1 exon
CGTCGAGCAGAACAGCCTCTGTATGGTTTAGATGGCAGTGCAGCAAAGGAGGCCTCAGAAGAGCAGTCTGCTCTGCCCACCCTCATGTCAGTGATGTTAGCAAAACCGCGACTTGACACAGAGCAGTTAGCGCCACGGGGAGCTGGCCTCTGCTTCACTTTCGTCTCT
Seq A exon
TCTGACCTCACAATAGAAAAAATATCTGCACTAGAAAACAGTAAGAACTCTGACTTAGAGAAGAAGGAAGGAAGAATAGATGATTTATTAAGA
Seq C2 exon
GCCAACTGTGATTTGAGACGACAGATAGATGAACAGCAAAAGATGCTAGAGAAATACAAGGAACGATTAAATAGATGTGTCACCATGAGCAAGAAGCTCCTTATAGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020694_MULTIEX2-2/3=C1-3
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.709 A=0.554 C2=0.046
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000118520





     
                   









    
Main Skipping Isoform:
ENSMUSP00000102554f818A





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000015107, ENSMUSP00000090198, ENSMUSP00000102549, ENSMUSP00000102552, ENSMUSP00000102554, ENSMUSP00000102554f819A, ENSMUSP00000123179
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr17:60631024-60631116 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr19:47625631-47625723 
HIGH PSI
BtaEX0036545
(TLK2)
Chicken
(galGal4)
chr27:2377439-2377531 
HIGH PSI
GgaEX1058702
(TLK2)
Chicken
(galGal3)
chr27:2285729-2285821 
HIGH PSI
GgaEX1058702
(TLK2)
Zebrafish
(danRer10)
chr3:19548156-19548248 
HIGH PSI
DreEX6016093
(tlk2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TAGCAAAACCGCGACTTGACA

				
R: 
GCTTCTTGCTCATGGTGACAC

				
Band lengths: 
168-261

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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