Special

MmuEX0051891 @ mm10

Exon Skipping

Gene
ENSMUSG00000035295 | Wdr38
Description
WD repeat domain 38 [Source:MGI Symbol;Acc:MGI:1923896]
Coordinates
chr2:38998337-39000089:+
Coord C1 exon
chr2:38998337-38998476
Coord A exon
chr2:38999283-38999403
Coord C2 exon
chr2:38999973-39000089
Length
121 bp
Sequences
Splice sites
3' ss Seq
TTTTTGCCCTGTACTTTCAGGTC
3' ss Score
11.26
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
Exon sequences
Seq C1 exon
GAACGGAGGCCCCTCCGACGGGACTGGTGCCCGCTTAGGAGGGAGCCCTCCGGGTTATGGAGTGGGCGCCCATGAACATCAGAGCCCCAACAAGATTGGCCGTGGGCAGAGTGAGGTTTTATGGTCAACACCACGGGGAG
Seq A exon
GTCAACTGCTCTGCCTTCTCTCCTGACGGCCGGACCCTGCTCACAGCCTCAGATGATGGCTGTGTGTATGTATGGGGGACAAAGAGTGGGCGACTGCTATGGAGACTGGCAGGCCACAGAG
Seq C2 exon
GCCCAGTGAAGTCTTGCTGTTTCTCTCCCGATGGCCGCCTCATTGCCAGCTCCTCCAGTGACCACAGCATCCGCCTGTGGGATGTGGCAAGGTCCAAGTGTCTACATGTGCTGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000035295-'2-5,'2-4,4-5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0040027=WD40=PU(27.0=35.7)

							
A:
PF0040027=WD40=PD(67.6=61.0),PF0040027=WD40=PU(28.2=26.8)

							
C2:
PF0040027=WD40=PD(69.2=67.5),PF0040027=WD40=PU(20.5=20.0)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000043834





     
                   









    
Main Skipping Isoform:
ENSMUST00000039535fB19493





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000108493
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr9:124854205-124854325 
HIGH PSI
HsaEX6062998
(WDR38)
Human
(hg19)
chr9:127616484-127616604 
HIGH PSI
HsaEX6062998
(WDR38)
Rat
(rn6)
chr3:23292234-23292354 
HIGH PSI
RnoEX0099172
(Wdr38)
Cow
(bosTau6)
chr11:95846743-95846863 
BtaEX6046116
(WDR38)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr21:5756594-5756714 
ALTERNATIVE
DreEX0085057
(wdr38)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCTCCGACGGGACTGGTG

				
R: 
CAGCACATGTAGACACTTGGACC

				
Band lengths: 
242-363

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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