Special

MmuEX0053915 @ mm10

Exon Skipping

Gene
ENSMUSG00000021945 | Zmym2
Description
zinc finger, MYM-type 2 [Source:MGI Symbol;Acc:MGI:1923257]
Coordinates
chr14:56925841-56932261:+
Coord C1 exon
chr14:56925841-56925957
Coord A exon
chr14:56928187-56928337
Coord C2 exon
chr14:56932089-56932261
Length
151 bp
Sequences
Splice sites
3' ss Seq
GGTTCCCGTTGTGCATTTAGAAC
3' ss Score
5.97
5' ss Seq
AAGGCAAGT
5' ss Score
3.24
Exon sequences
Seq C1 exon
GCTCTAAGCATGCAGTCATCTCCAAATGGCCAGTTTGTAGCACCCAGTGATATTCAGCTGAAATGCAACTACTGTAAAAATTCCTTTTGTTCAAAACCAGAAATCTTGGAATGGGAG
Seq A exon
AACAAAGTGCATCAGTTCTGCAGCAAAACTTGCTCAGATGACTATAAGAAGTTGCATTGCATAGTTACATATTGCGAATACTGCCAAGAGGAGAAGACTCTGCATGAAACAGTAAATTTCTCTGGCGTTAAGAGACCTTTCTGTAGTGAAG
Seq C2 exon
GCTGCAAGCTATTATACAAACAAGATTTTGCAAGACGATTAGGATTAAGATGTGTTACCTGCAACTATTGTTCTCAGCTGTGTAAGAAGGGAGCCACTAAAGAACTTGATGGAGTTGTCAGAGACTTCTGCAGTGAAGACTGCTGTAAGAAATTCCAGGAGTGGTACTACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000021945_CASSETTE3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF064679=zf-FCS=PU(61.0=64.1)

							
A:
PF064679=zf-FCS=PD(34.1=27.5),PF064679=zf-FCS=PU(85.0=66.7)

							
C2:
PF064679=zf-FCS=PD(12.5=8.6),PF064679=zf-FCS=WD(100=69.0),PF064679=zf-FCS=PU(10.0=6.9)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000022511





     
                   









    
Main Skipping Isoform:
ENSMUST00000022511fB20105





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr13:20034254-20034404 
ALTERNATIVE
HsaEX0072884
(ZMYM2)
Human
(hg19)
chr13:20608394-20608544 
HIGH PSI
HsaEX0072884
(ZMYM2)
Rat
(rn6)
chr15:37198128-37198278 
HIGH PSI
RnoEX0102015
(Zmym2)
Cow
(bosTau6)
chr12:36414375-36414525 
ALTERNATIVE
BtaEX0041035
(ZMYM2)
Chicken
(galGal4)
chr1:178310939-178311089 
HIGH PSI
GgaEX6006360
([1])
Chicken
(galGal3)
chr1:183367056-183367206 
HIGH PSI
GgaEX6006360
([2])
Zebrafish
(danRer10)
chr9:21632778-21632928 
HIGH PSI
DreEX6035995
(zmym2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCAGTCATCTCCAAATGGCCA

				
R: 
CAGTCTTCACTGCAGAAGTCTCT

				
Band lengths: 
248-399

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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