Special

MmuEX0054050 @ mm9

Exon Skipping

Gene
ENSMUSG00000036721 | Zscan12
Description
zinc finger and SCAN domain containing 12 [Source:MGI Symbol;Acc:MGI:1099444]
Coordinates
chr13:21455449-21461693:+
Coord C1 exon
chr13:21455449-21455920
Coord A exon
chr13:21458484-21458625
Coord C2 exon
chr13:21460421-21461693
Length
142 bp
Sequences
Splice sites
3' ss Seq
GCTTCTCCCATTTCCCCCAGGCC
3' ss Score
10.33
5' ss Seq
AAGGTAAAG
5' ss Score
9.06
Exon sequences
Seq C1 exon
GTCCACTGGGTAAGAAGATTTACCAAGGAGTTATTACTTGAAAGATTGATACATCTTTTATCTAGCTACGATGACATCTACTAGTGATACCAAGGTCTGTAAGAACCAGGGTGGACTTTTGGAAATAAAAATGGAGGAAGAATGTAAGTATACCACCAGACAAGATAGGAACCTACAAAAGAACACTTATAACAGAGACGTCTTCCGAAAATACTTCAGACAGTTTTGCTACCAGGAAACTTCTGGACCCCGGGAGGCTCTGAGCCGGCTGCGCGAGCTCTGCAGACAGTGGCTGCGGCCGGACTTGAACAGCAAGGAGCAGATCCTGGAGCTGCTGGTGCTGGAGCAGTTCCTGACCATCCTGCCAGGGGAGCTGCAGGCCTGGGTGCAGGAGCAGAATCCGGAGAGTGTGGAGGAGGTGGTGACTGTGCTGGAGGATTTAGAGAGAGAGCTTGATGAACTAGGATACCGG
Seq A exon
GCCTCAGTCCAAACTGAAGAACAGGTAACGTTTCAGGAGGTGAAGCCTTTGGCAACAGAGCAGAAACCCAGCGTGTCCCTTCAGTTTGTCAAAGCCAAGCCTGGGTGTGAACTTGCAGGCCGTGAAGCCCAGGAGGAGCAAG
Seq C2 exon
TTTCAGGTGTTGAGACTGGCAATGAGCCCAGGAATGTCACTCTAAAGCAAGGCCTCTGGGAAGGGACGGAAGCAGAACAGAATCCTGCTAGCAGATTAGCAAAGGATGCACTTGAGTGTGAAGAAGCTCACAACCCTGGAGAAGAGTCTTCTGGTATTTCCCATGAAGACAGCCAGCCTCTGCGTAATGAAAATGGTGTAAATTCTCCTGCGAACTCAGAGTACGCTAAACACCAGAGCATCTGTCCAGGGAGAAAAGTGCATGGGTGTGATGAGTGTGGAAAGAGTTTTACTCAGCACTCGCGCCTCATAGAGCACAAGAGAGTCCACACTGGAGACAGGCCCTACAAATGTGAAGTATGTGGGAAAACTTTCCGATGGAGGACTGTTCTTATTCGACACAAGGTGGTCCACACTGGAGAGAAACCGTATAAATGTAATGAATGTGGCAGGGCTTTTGGCCAGTGGTCAGCACTTAACCAACATCAGAGACTTCACTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000036721-'1-3,'1-2,2-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.030 A=0.354 C2=0.353
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0202312=SCAN=PU(97.9=70.1)

							
A:
PF0202312=SCAN=PD(0.1=0.0)

							
C2:
PF134651=zf-H2C2_2=WD(100=7.8),PF134651=zf-H2C2_2=WD(100=8.1),PF134651=zf-H2C2_2=WD(100=7.5),PF134651=zf-H2C2_2=WD(100=8.1),PF134651=zf-H2C2_2=WD(100=8.1),PF134651=zf-H2C2_2=WD(100=6.5),PF134651=zf-H2C2_2=WD(100=8.1)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000058904





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000097308
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr6:28392902-28393046 
HIGH PSI
HsaEX0074551
(ZSCAN12)
Human
(hg19)
chr6:28360679-28360823 
HIGH PSI
HsaEX0074551
(ZSCAN12)
Rat
(rn6)
chr17:45281153-45281297 
ALTERNATIVE
RnoEX0102287
(Zscan12)
Cow
(bosTau6)
chr23:30086981-30087119 
HIGH PSI
BtaEX6098752
(ZSCAN12)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AATCCGGAGAGTGTGGAGGAG

				
R: 
CAGAGGCTGGCTGTCTTCATG

				
Band lengths: 
257-399

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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