Special

MmuEX1008792 @ mm10

Exon Skipping

Gene
ENSMUSG00000033335 | Dnm2
Description
dynamin 2 [Source:MGI Symbol;Acc:MGI:109547]
Coordinates
chr9:21505464-21507754:+
Coord C1 exon
chr9:21505464-21505715
Coord A exon
chr9:21506333-21506562
Coord C2 exon
chr9:21507423-21507754
Length
230 bp
Sequences
Splice sites
3' ss Seq
TATCTTTACTTTCTTTGCAGCAG
3' ss Score
9.28
5' ss Seq
AGGGTGAGG
5' ss Score
7.13
Exon sequences
Seq C1 exon
CCCCACTCCACAGCGCCGACCTGTGTCCAGTGTGCACCCACCAGGCCGGCCACCTGCAGTGCGGGGTCCTACACCGGGGCCTCCCCTGATTCCTATGCCTGTGGGGGCCACATCCTCCTTCTCAGCACCTCCCATCCCATCCCGGCCTGGACCACAGAGTGTGTTTGCCAACAACGACCCCTTCTCTGCGCCACCTCAGATACCATCTCGGCCAGCACGGATTCCCCCTGGTATCCCTCCAGGAGTGCCCAG
Seq A exon
CAGAAGAGCGCCCGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCCGAGCCGTCCCTGCTCGACTAGGCTGCAGGGGGCAATGTTCTGGGGGGGTCCTCGTGCACCCACAGTGTAGGACAGTTTTGGTGGTCTGGGCCCTGCTACTTGCCCTCCATGCTGGGACCAGGCTCCCCGTGGGCAAGCCCTGCCCTTTCCCTCCTCGCCCTAGTGGACATGACAATGAAGG
Seq C2 exon
GCGACCACCTCCATTGGCTCCTGCCCGACCTTTCTTCTGAGCTTCGTGGGAGTGTCCCCCCTTCCTGGCTGCCCTGGCTTGAGGCTAGGTCTGTCCCAAGCTGACATCCCTAAGCCCAGTCACCAGGCACTATTAACTTTCTGACCATAATTTATTGACTCCAGTGCCCAGGACAAATGCCCTCTGTTCCTTGAGGCTCATGGGCCAGCCTTCTCTGAGGCCCTGCACCCAGAGAGAAGGAAGGGGCCTCTCCCAAACCACCTACTAGCTGGCTCCCCTCTGGGCCAAGGGGCCAGGGCTCCTTCCTTTCAAATAAAAGTGACTGTCCTGGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000033335_CASSETTE3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=1.000 A=1.000 C2=1.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUST00000165766fB8981





     
                   









    
Main Skipping Isoform:
ENSMUSP00000128961





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000072199, ENSMUSP00000088616, ENSMUSP00000111063, ENSMUSP00000133564, ENSMUSP00000134243
          









    
Other Skipping Isoforms:
ENSMUSP00000134696
  



Associated events







Conservation


Human
(hg38)
chr19:10830978-10831237 
Human
(hg19)
chr19:10941654-10941913 
Rat
(rn6)
chr8:22539224-22539440 
Cow
(bosTau6)
chr7:16522400-16522658 
Chicken
(galGal4)
chr17:5017963-5018094 
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr3:50401899-50401970 
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GACCACAGAGTGTGTTTGCCA

				
R: 
CCCATGAGCCTCAAGGAACAG

				
Band lengths: 
307-537

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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