MmuEX6064376 @ mm10
Exon Skipping
Gene
ENSMUSG00000033335 | Dnm2
Description
dynamin 2 [Source:MGI Symbol;Acc:MGI:109547]
Coordinates
chr9:21504430-21507754:+
Coord C1 exon
chr9:21504430-21504662
Coord A exon
chr9:21505464-21505715
Coord C2 exon
chr9:21507423-21507754
Length
252 bp
Sequences
Splice sites
3' ss Seq
AGCCTTTCCTTCCTCCATAGCCC
3' ss Score
9.05
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
Exon sequences
Seq C1 exon
ACAAAGGCCTTCATCCACCATGAGCTGCTGGCTTACCTGTATTCATCAGCAGACCAGAGCAGCCTCATGGAAGAGTCAGCCGAGCAGGCTCAGCGGCGGGACGACATGCTGCGCATGTACCACGCACTGAAGGAGGCCCTCAACATTATTGGGGACATCAGCACCAGCACCGTGTCCACACCCGTGCCCCCACCGGTCGATGACACGTGGCTCCAAAACACCAGCGGCCACAG
Seq A exon
CCCCACTCCACAGCGCCGACCTGTGTCCAGTGTGCACCCACCAGGCCGGCCACCTGCAGTGCGGGGTCCTACACCGGGGCCTCCCCTGATTCCTATGCCTGTGGGGGCCACATCCTCCTTCTCAGCACCTCCCATCCCATCCCGGCCTGGACCACAGAGTGTGTTTGCCAACAACGACCCCTTCTCTGCGCCACCTCAGATACCATCTCGGCCAGCACGGATTCCCCCTGGTATCCCTCCAGGAGTGCCCAG
Seq C2 exon
GCGACCACCTCCATTGGCTCCTGCCCGACCTTTCTTCTGAGCTTCGTGGGAGTGTCCCCCCTTCCTGGCTGCCCTGGCTTGAGGCTAGGTCTGTCCCAAGCTGACATCCCTAAGCCCAGTCACCAGGCACTATTAACTTTCTGACCATAATTTATTGACTCCAGTGCCCAGGACAAATGCCCTCTGTTCCTTGAGGCTCATGGGCCAGCCTTCTCTGAGGCCCTGCACCCAGAGAGAAGGAAGGGGCCTCTCCCAAACCACCTACTAGCTGGCTCCCCTCTGGGCCAAGGGGCCAGGGCTCCTTCCTTTCAAATAAAAGTGACTGTCCTGGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000033335-'66-63,'66-60,74-63
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.550 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
PF0221213=GED=PD(56.5=66.7)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGCAGCCTCATGGAAGAGT
R:
TGGGCTTAGGGATGTCAGCTT
Band lengths:
296-548
Functional annotations
There are 1 annotated functions for this event
PMID: 15483625
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: competition binding, glutathione s tranferase tag, nuclear magnetic resonance, pull down, surface plasmon resonance. ELM ID: ELMI002131; ELM sequence: PQIPSR; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types