MmuEX6064376 @ mm9
Exon Skipping
Gene
ENSMUSG00000033335 | Dnm2
Description
dynamin 2 [Source:MGI Symbol;Acc:MGI:109547]
Coordinates
chr9:21308874-21311568:+
Coord C1 exon
chr9:21308874-21309106
Coord A exon
chr9:21309908-21310159
Coord C2 exon
chr9:21310777-21311568
Length
252 bp
Sequences
Splice sites
3' ss Seq
AGCCTTTCCTTCCTCCATAGCCC
3' ss Score
9.05
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
Exon sequences
Seq C1 exon
ACAAAGGCCTTCATCCACCATGAGCTGCTGGCTTACCTGTATTCATCAGCAGACCAGAGCAGCCTCATGGAAGAGTCAGCCGAGCAGGCTCAGCGGCGGGACGACATGCTGCGCATGTACCACGCACTGAAGGAGGCCCTCAACATTATTGGGGACATCAGCACCAGCACCGTGTCCACACCCGTGCCCCCACCGGTCGATGACACGTGGCTCCAAAACACCAGCGGCCACAG
Seq A exon
CCCCACTCCACAGCGCCGACCTGTGTCCAGTGTGCACCCACCAGGCCGGCCACCTGCAGTGCGGGGTCCTACACCGGGGCCTCCCCTGATTCCTATGCCTGTGGGGGCCACATCCTCCTTCTCAGCACCTCCCATCCCATCCCGGCCTGGACCACAGAGTGTGTTTGCCAACAACGACCCCTTCTCTGCGCCACCTCAGATACCATCTCGGCCAGCACGGATTCCCCCTGGTATCCCTCCAGGAGTGCCCAG
Seq C2 exon
CAGAAGAGCGCCCGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCCGAGCCGTCCCTGCTCGACTAGGCTGCAGGGGGCAATGTTCTGGGGGGGTCCTCGTGCACCCACAGTGTAGGACAGTTTTGGTGGTCTGGGCCCTGCTACTTGCCCTCCATGCTGGGACCAGGCTCCCCGTGGGCAAGCCCTGCCCTTTCCCTCCTCGCCCTAGTGGACATGACAATGAAGGGTGAGGAGGCCCACAGCACAGCACATGGGGGCTTTGCACTTTGGGATGAGGAGGAGCTCTGGCTAGCAGAACAGGAACTGCATCCTTGGGACCATCAGGAAAAAAAGGTCCAGGCTAGTGTGGGGGGACTCTTCTGGAGCTCCTCCAGAGCCTTTGTTCTTTCTGGGGTCCAGGAACTGCCCACCTTTCCTAAGGACTCCTCAGGAGTGAGCCAGGCCCAGCAGGTCCAGTGCTGACCCACCTGGCTCAAGTTGTATATATAGAGCTCCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000033335-'27-27,'27-26,28-27=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.551 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
PF0221213=GED=PD(56.5=66.7)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGACACGTGGCTCCAAAACA
R:
AAAGTGCAAAGCCCCCATGTG
Band lengths:
306-558
Functional annotations
There are 1 annotated functions for this event
PMID: 15483625
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: competition binding, glutathione s tranferase tag, nuclear magnetic resonance, pull down, surface plasmon resonance. ELM ID: ELMI002131; ELM sequence: PQIPSR; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: