MmuEX1015750 @ mm10
Exon Skipping
Gene
ENSMUSG00000007670 | Khsrp
Description
KH-type splicing regulatory protein [Source:MGI Symbol;Acc:MGI:1336214]
Coordinates
chr17:57025496-57026914:-
Coord C1 exon
chr17:57026843-57026914
Coord A exon
chr17:57025880-57025933
Coord C2 exon
chr17:57025496-57025670
Length
54 bp
Sequences
Splice sites
3' ss Seq
CTCTTCTTCTCCACAGATAGTGG
3' ss Score
0.36
5' ss Seq
CCAGTAAGT
5' ss Score
9.09
Exon sequences
Seq C1 exon
TTATTGGCAGAGGTGGTGAGCAGATAAACAAAATCCAGCAGGACTCAGGCTGCAAAGTTCAGATCTCACCAG
Seq A exon
TGGTGGCCTCCCTGAGCGCAGCGTGTCTCTGACTGGAGCACCTGAGTCTGTCCA
Seq C2 exon
AAAGGCAAAGATGATGCTGGATGACATCGTGTCTCGGGGCCGTGGTGGCCCCCCAGGACAGTTTCACGACAACGCCAATGGGGGTCAGAATGGCACAGTGCAGGAGATCATGATCCCTGCTGGCAAGGCTGGCCTGGTCATTGGTAAAGGTGGAGAGACCATCAAGCAGCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000007670-'13-8,'13-7,14-8
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.800 A=0.950 C2=0.593
Domain overlap (PFAM):
C1:
PF0001324=KH_1=FE(38.1=100)
A:
PF0001324=KH_1=FE(30.2=100)
C2:
PF0001324=KH_1=PD(9.5=10.2),PF0001324=KH_1=PU(38.5=42.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGGACTCAGGCTGCAAAGTT
R:
ATCTCCTGCACTGTGCCATTC
Band lengths:
142-196
Functional annotations
There are 1 annotated functions for this event
PMID: 19770516
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002009; ELM sequence: VQISPD; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types