BtaEX6038729 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000021018 | KHSRP
Description
KH-type splicing regulatory protein [Source:HGNC Symbol;Acc:HGNC:6316]
Coordinates
chr7:19264697-19266024:+
Coord C1 exon
chr7:19264697-19264768
Coord A exon
chr7:19265504-19265561
Coord C2 exon
chr7:19265850-19266024
Length
58 bp
Sequences
Splice sites
3' ss Seq
CTCTCCACTCCTCTCTCCAGACA
3' ss Score
8.86
5' ss Seq
GCAGTAAGT
5' ss Score
9.07
Exon sequences
Seq C1 exon
TCATCGGCAGAGGAGGTGAACAGATTAACAAAATCCAGCAGGACTCAGGCTGCAAAGTCCAAATCTCTCCAG
Seq A exon
ACAGCGGTGGCCTACCTGAACGCAGTGTGTCCTTGACAGGAGCCCCGGAATCTGTGCA
Seq C2 exon
GAAAGCGAAGATGATGCTGGACGACATTGTCTCCCGGGGCCGTGGGGGGCCCCCGGGCCAGTTCCACGACAACGCCAACGGGGGCCAGAACGGCACAGTGCAGGAGATCATGATCCCCGCGGGCAAGGCTGGCCTGGTCATTGGCAAGGGCGGGGAGACCATCAAGCAGCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000021018-'7-11,'7-9,8-11=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.800 A=0.950 C2=0.593
Domain overlap (PFAM):
C1:
PF0001324=KH_1=FE(38.1=100)
A:
PF0001324=KH_1=FE(30.2=100)
C2:
PF0001324=KH_1=PD(9.5=10.2),PF0001324=KH_1=PU(38.5=42.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACTCAGGCTGCAAAGTCCAA
R:
CATGATCTCCTGCACTGTGCC
Band lengths:
143-201
Functional annotations
There are 1 annotated functions for this event
PMID: 19770516
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002009; ELM sequence: VQISPD; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]