DreEX6033894 @ danRer10
Exon Skipping
Gene
ENSDARG00000026489 | khsrp
Description
KH-type splicing regulatory protein [Source:ZFIN;Acc:ZDB-GENE-030131-4357]
Coordinates
chr1:54289488-54289973:-
Coord C1 exon
chr1:54289902-54289973
Coord A exon
chr1:54289741-54289798
Coord C2 exon
chr1:54289488-54289653
Length
58 bp
Sequences
Splice sites
3' ss Seq
TCTCACTGTTTGTGTTTCAGACA
3' ss Score
10.7
5' ss Seq
CCAGTATGT
5' ss Score
5.8
Exon sequences
Seq C1 exon
TCATTGGTCGAGGTGGCGAGCAGATCAATAAGATCCAGCAGGACTCTGGTTGTAAAGTTCAGATCGCTCCAG
Seq A exon
ACAGTGGCGGTCTTCCAGACAGAAGTGTGTCCATCACAGGAGGCCCTGAAGCCATCCA
Seq C2 exon
GAAGGCCAAAATGATGCTGGACGACATCGTCTCTCGGGGGCGGGGCACTCCGCCTTCCTTTCATGAGTCGACCAATGGGAGTGGCCACATGCAGGAAATGGTCATTCCAGCAGGGAAGGCTGGTCTCATTATTGGCAAAGGAGGAGAGACCATTAAACAGCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000026489-'7-9,'7-7,8-9=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.640 A=0.932 C2=0.562
Domain overlap (PFAM):
C1:
PF0001324=KH_1=FE(38.1=100)
A:
PF0001324=KH_1=PD(32.1=90.0)
C2:
PF0001324=KH_1=PD(9.5=10.7),PF0001324=KH_1=PU(38.5=44.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGTGGCGAGCAGATCAATA
R:
CGACTCATGAAAGGAAGGCGG
Band lengths:
133-191
Functional annotations
There are 1 annotated functions for this event
PMID: 19770516
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002009; ELM sequence: VQISPD; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]