MmuEX1024553 @ mm10
Exon Skipping
Gene
ENSMUSG00000001280 | Sp1
Description
trans-acting transcription factor 1 [Source:MGI Symbol;Acc:MGI:98372]
Coordinates
chr15:102407772-102408460:+
Coord C1 exon
chr15:102407772-102407932
Coord A exon
chr15:102408216-102408235
Coord C2 exon
chr15:102408360-102408460
Length
20 bp
Sequences
Splice sites
3' ss Seq
CTTTCCTCTCTTCTGGCCAGGAA
3' ss Score
9.3
5' ss Seq
TTTGGCTCT
5' ss Score
-26.42
Exon sequences
Seq C1 exon
ACCAAGATCACTCCATGGATGAAGTGACAGCTGTGGTGAAGATTGAAAAAGATGTTGGTGGCAATAATGGGGGTAGCGGCAATGGTGGCGGTGCCGCCTTTTCTCAGACTCGAAGCAGCAGCACAGGCAGTAGCAGCAGCAGTGGTGGCGGAGGAGGGCAG
Seq A exon
GAATCCCAGCCATCTCCTTT
Seq C2 exon
GGTGCCAATGGCTGGCAGATCATCTCTTCCTCCTCTGGGGCTACCCCTACCTCAAAGGAACAGAGTGGCAACAGTACCAATGGCAGCGAGTCTTCCAAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000001280-'6-8,'6-7,7-8
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=0.587 C2=NA
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGCCGCCTTTTCTCAGACTC
R:
GTAGCCCCAGAGGAGGAAGAG
Band lengths:
115-135
Functional annotations
There are 1 annotated functions for this event
PMID: 11904305
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: classical fluorescence spectroscopy, mutation analysis, protein kinase assay. ELM ID: ELMI001445; ELM sequence: IIRTPTV; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types