MmuEX6007455 @ mm9
Exon Skipping
Gene
ENSMUSG00000030201 | Lrp6
Description
low density lipoprotein receptor-related protein 6 [Source:MGI Symbol;Acc:MGI:1298218]
Coordinates
chr6:134436473-134457700:-
Coord C1 exon
chr6:134457304-134457700
Coord A exon
chr6:134456214-134456385
Coord C2 exon
chr6:134436473-134436689
Length
172 bp
Sequences
Splice sites
3' ss Seq
TTGATTTTCTGTCTTTATAGGTA
3' ss Score
11.08
5' ss Seq
GAGGTTTGT
5' ss Score
6.36
Exon sequences
Seq C1 exon
GTGCCACTGAACTATTGCTGTTAGCCCGACGGACAGACTTGAGGCGAATTTCTTTGGATACACCCGATTTTACTGACATTGTTCTGCAGTTAGAAGATATCCGGCATGCCATTGCCATAGACTATGACCCTGTAGAAGGCTACATATACTGGACGGATGACGAAGTGAGGGCTATCCGTCGCTCCTTCATAGATGGATCTGGCAGTCAGTTTGTGGTCACGGCCCAGATTGCTCATCCTGATGGTATTGCTGTTGACTGGGTTGCAAGGAACCTGTACTGGACAGACACTGGCACGGATCGTATAGAAGTGACAAGGCTCAATGGGACCATGAGGAAGATCTTGATTTCAGAGGACTTAGAGGAGCCCCGGGCTATCGTGTTAGATCCCATGGTTGG
Seq A exon
GTACATGTATTGGACAGACTGGGGAGAAATCCCAAAAATAGAGCGAGCTGCTCTGGACGGATCTGACCGAGTAGTTCTTGTCAACACTTCCCTTGGTTGGCCAAACGGCTTAGCCCTGGATTATGATGAAGGCACAATATACTGGGGAGATGCCAAAACAGACAAAATTGAG
Seq C2 exon
GTTATGAATACCGATGGCACCGGGAGGCGAGTGCTGGTGGAAGACAAGATCCCTCACATATTTGGGTTTACCTTGCTGGGTGACTATGTTTACTGGACTGACTGGCAGAGGCGGAGCATCGAGAGAGTACACAAACGGAGCGCAGAGAGGGAGGTCATCATAGATCAGCTGCCAGACCTCATGGGACTGAAGGCCACAAGTGTTCACAGAATCATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030201-'8-9,'8-7,9-9=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=WD(100=72.4),PF0005812=Ldl_recept_b=PU(33.3=22.4)
C2:
PF0005812=Ldl_recept_b=PD(61.5=32.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGACTGGGTTGCAAGGAACC
R:
CCTCTGCCAGTCAGTCCAGTA
Band lengths:
256-428
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: