MmuEX6009973 @ mm10
Exon Skipping
Gene
ENSMUSG00000001249 | Hpn
Description
hepsin [Source:MGI Symbol;Acc:MGI:1196620]
Coordinates
chr7:31102478-31103194:-
Coord C1 exon
chr7:31103154-31103194
Coord A exon
chr7:31102761-31102926
Coord C2 exon
chr7:31102478-31102668
Length
166 bp
Sequences
Splice sites
3' ss Seq
TCCTTGTCACCTCTCCACAGACT
3' ss Score
10.05
5' ss Seq
AGAGTGAGT
5' ss Score
7.36
Exon sequences
Seq C1 exon
TGACTGTCCTAGAGGCCGATTCCTGACTGCCACCTGCCAAG
Seq A exon
ACTGTGGCCGCAGGAAGCTGCCGGTGGACCGCATTGTGGGGGGCCAGGACAGCAGTCTGGGAAGGTGGCCGTGGCAGGTCAGCCTGCGTTATGATGGGACCCACCTCTGTGGGGGGTCCCTGCTGTCTGGGGACTGGGTGCTGACTGCTGCACATTGCTTTCCAGA
Seq C2 exon
GCGGAACCGGGTCCTGTCTCGGTGGCGAGTATTTGCTGGTGCTGTAGCCCGGACCTCACCCCATGCTGTGCAACTGGGGGTTCAGGCTGTGATCTATCATGGGGGCTACCTTCCCTTTCGAGACCCTACTATCGACGAAAACAGCAATGACATTGCCTTGGTCCACCTCTCTAGCTCCCTGCCTCTCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000001249-'18-23,'18-22,20-23=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF092725=Hepsin-SRCR=PD(46.1=95.3)
A:
PF092725=Hepsin-SRCR=PD(6.4=12.5),PF0008921=Trypsin=PU(18.5=78.6)
C2:
PF0008921=Trypsin=FE(26.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGTCCTAGAGGCCGATTCC
R:
GAGAGGCAGGGAGCTAGAGAG
Band lengths:
226-392
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types