Special

MmuEX6019719 @ mm9

Exon Skipping

Gene
ENSMUSG00000058153 | Sez6l
Description
seizure related 6 homolog like [Source:MGI Symbol;Acc:MGI:1935121]
Coordinates
chr5:112901751-112904606:-
Coord C1 exon
chr5:112904049-112904606
Coord A exon
chr5:112902438-112902571
Coord C2 exon
chr5:112901751-112901943
Length
134 bp
Sequences
Splice sites
3' ss Seq
CAATGTTTGTTTCTCTGTAGCTC
3' ss Score
8.3
5' ss Seq
CAGGTAGCC
5' ss Score
7.13
Exon sequences
Seq C1 exon
GCTGGAGAGTAGCCTGGAAGAGGGGGTGACATCAGCAGCCCCAGGTCTCCTGCCATCCCAAGAAGCACTGGAAGCAATGGAAGAGTCCTTGCCCCCTGCGCTGCCCGACGAGGCCAGTGTCCAGCACACGCCTGCCCTAAGGAAGGGTCTGCCGTCCCTGAAGCAACTCAACTCGGCCCGGAGGCAGCTGAGGCCCCTGGCTACCCCGACAACTCTGCAGAGACTGGGGTCTCCTGCCTCTGCCACCACGAAGCTGCGTGAGCCTGAAGACCCCGAGCAGCCCACGGCGCCTGCGCCACTGCAGATCGCGCCCTTCACTGCACTGGCGACCACACTCCCACACAGCCCTCAGCCCGCTCAGGCCCCTGATGACAGCAGCCCCGGTAGCCCGCTGGACAAGGGGGACAATGAGCTGACCGGGTCTGCCTCCGAGGAGAGCCAGGAGACCACCACGTCCACCATCGTCACTACCACCATCATCACCACGGAGCAGGCCCCAG
Seq A exon
CTCTCTGCGGTGTGAGCTTCTCCGACCCGGAGGGATACATTGACTCAAGTGATTTCCCTCCACAACCCTACAGCAGCTTCCTGGAATGCACTTACAATGTGACGGTCTACACTGGCTACGGGGTGGAACTGCAG
Seq C2 exon
GTCAAGAGTGTCAACCTCTCCGAGGGGGAGCTGCTCTCCATCCGAGGAGTGGACGGTCCCACTCTGACAGTCCTGGCCAACCAGACTCTACTGGTAGAGGGCCAGGTGATCCGCAGCCCCACCAACACCATCTCTGTCTACTTCCGGACCTTCCAGGATGATGGCCTCGGGACCTTCCAGCTACATTACCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000058153-'1-2,'1-1,2-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.944 A=0.133 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
PF0043115=CUB=PU(39.6=93.3)

							
C2:
PF0043115=CUB=PD(58.5=95.4)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000074847





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000078454, ENSMUSP00000098442
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr22:26294292-26294425 
HIGH PSI
HsaEX6026182
(SEZ6L)
Human
(hg19)
chr22:26690258-26690391 
HIGH PSI
HsaEX6026182
(SEZ6L)
Rat
(rn6)
chr12:50191315-50191448 
HIGH PSI
RnoEX6065080
(Sez6l)
Cow
(bosTau6)
chr17:68251170-68251303 
HIGH PSI
BtaEX6073577
(SEZ6L)
Chicken
(galGal4)
chr15:7124629-7124762 
HIGH PSI
GgaEX1052038
(SEZ6L)
Chicken
(galGal3)
chr15:7343747-7343880 
HIGH PSI
GgaEX1052038
(SEZ6L)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CAAGGGGGACAATGAGCTGAC

				
R: 
GACAGAGATGGTGTTGGTGGG

				
Band lengths: 
242-376

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]










Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"