Special

MmuEX6026012 @ mm10

Exon Skipping

Gene
ENSMUSG00000026251 | Chrnd
Description
cholinergic receptor, nicotinic, delta polypeptide [Source:MGI Symbol;Acc:MGI:87893]
Coordinates
chr1:87192486-87195000:+
Coord C1 exon
chr1:87192486-87192641
Coord A exon
chr1:87192846-87192955
Coord C2 exon
chr1:87194800-87195000
Length
110 bp
Sequences
Splice sites
3' ss Seq
ATGACCACTGCTCTCTCCAGTTC
3' ss Score
6.18
5' ss Seq
CAGGTACTT
5' ss Score
8.17
Exon sequences
Seq C1 exon
CAATGATGGCTCGTTCCAGATTTCTTATGCCTGCAATGTGCTTGTCTATGACTCGGGCTATGTGACCTGGCTGCCGCCCGCCATCTTCCGCTCCTCCTGCCCCATCTCAGTCACCTACTTCCCTTTCGACTGGCAGAACTGCTCCCTCAAATTCAG
Seq A exon
TTCACTCAAGTATACAGCCAAGGAGATCACACTTAGCCTGAAGCAGGAGGAGGAAAACAACCGCTCTTACCCCATCGAGTGGATCATCATTGACCCTGAAGGTTTCACAG
Seq C2 exon
AGAACGGTGAGTGGGAGATAGTGCATCGGGCAGCCAAGCTCAATGTGGACCCCAGTGTCCCGATGGACAGCACCAACCACCAAGATGTCACCTTCTACCTTATCATCCGCCGCAAGCCCCTCTTCTACATCATCAACATTCTGGTACCCTGCGTGCTCATCTCCTTCATGATCAACCTAGTCTTCTACCTGCCAGGCGACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026251_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0293118=Neur_chan_LBD=FE(23.4=100)

							
A:
PF0293118=Neur_chan_LBD=FE(16.7=100)

							
C2:
PF0293118=Neur_chan_LBD=PD(17.6=57.4),PF0293211=Neur_chan_memb=PU(8.9=30.9)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000072983





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000139537
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr2:232528862-232528971 
ALTERNATIVE
HsaEX0015329
(CHRND)
Human
(hg19)
chr2:233393572-233393681 
ALTERNATIVE
HsaEX0015329
(CHRND)
Rat
(rn6)
chr9:94288683-94288792 
HIGH PSI
RnoEX6040757
(Chrnd)
Cow
(bosTau6)
chr2:120977036-120977145 
HIGH PSI
BtaEX6012176
(CHRND)
Chicken
(galGal4)
chr9:15077595-15077710 
HIGH PSI
GgaEX6046375
(CHRND)
Chicken
(galGal3)
chr9:16707426-16707541 
HIGH PSI
GgaEX6046375
(F1NJ26_CHICK)
Zebrafish
(danRer10)
chr24:25543522-25543631 
HIGH PSI
DreEX0021721
(chrnd)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ATGCCTGCAATGTGCTTGTCT

				
R: 
TGCGGCGGATGATAAGGTAGA

				
Band lengths: 
244-354

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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