MmuEX6030291 @ mm10
Exon Skipping
Gene
ENSMUSG00000024913 | Lrp5
Description
low density lipoprotein receptor-related protein 5 [Source:MGI Symbol;Acc:MGI:1278315]
Coordinates
chr19:3652133-3686556:-
Coord C1 exon
chr19:3686355-3686556
Coord A exon
chr19:3659244-3659640
Coord C2 exon
chr19:3652133-3652330
Length
397 bp
Sequences
Splice sites
3' ss Seq
ACCCTGTGCTCTGCCCACAGCCT
3' ss Score
10.4
5' ss Seq
TGGGTAAAC
5' ss Score
3.32
Exon sequences
Seq C1 exon
GGGCCGCGGCGCCCGAGGCGGGAGCAAGAGGCGCCGGGAGCCGCGAGGATCCACCGCCGCCGCGCGCGCCATGGAGCCCGAGTGAGCGCGCGGCGCTCCCGGCCGCCGGACGACATGGAAACGGCGCCGACCCGGGCCCCTCCGCCGCCGCCGCCGCCGCTGCTGCTGCTGGTGCTGTACTGCAGCTTGGTCCCCGCCGCGG
Seq A exon
CCTCACCGCTCCTGTTGTTTGCCAACCGCCGGGATGTGCGGCTAGTGGATGCCGGCGGAGTGAAGCTGGAGTCCACCATTGTGGCCAGTGGCCTGGAGGATGCAGCTGCTGTAGACTTCCAGTTCTCCAAGGGTGCTGTGTACTGGACAGATGTGAGCGAGGAGGCCATCAAACAGACCTACCTGAACCAGACTGGAGCTGCTGCACAGAACATTGTCATCTCGGGCCTCGTGTCACCTGATGGCCTGGCCTGTGACTGGGTTGGCAAGAAGCTGTACTGGACGGACTCCGAGACCAACCGCATTGAGGTTGCCAACCTCAATGGGACGTCCCGTAAGGTTCTCTTCTGGCAGGACCTGGACCAGCCAAGGGCCATTGCCCTGGATCCTGCACATGG
Seq C2 exon
GTACATGTACTGGACTGACTGGGGGGAAGCACCCCGGATCGAGCGGGCAGGGATGGATGGCAGTACCCGGAAGATCATTGTAGACTCCGACATTTACTGGCCCAATGGGCTGACCATCGACCTGGAGGAACAGAAGCTGTACTGGGCCGATGCCAAGCTCAGCTTCATCCACCGTGCCAACCTGGACGGCTCCTTCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024913-'0-3,'0-1,10-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.333 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=62.7),PF0005812=Ldl_recept_b=PU(56.4=32.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCATGGAGCCCGAGTGAGC
R:
GGAAGGAGCCGTCCAGGTT
Band lengths:
331-728
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types