MmuEX6035190 @ mm10
Exon Skipping
Gene
ENSMUSG00000031492 | Chrnb3
Description
cholinergic receptor, nicotinic, beta polypeptide 3 [Source:MGI Symbol;Acc:MGI:106212]
Coordinates
chr8:27393300-27399730:+
Coord C1 exon
chr8:27393300-27393409
Coord A exon
chr8:27393614-27394496
Coord C2 exon
chr8:27396660-27399730
Length
883 bp
Sequences
Splice sites
3' ss Seq
GGTAACCACTTTCATGGCAGTGC
3' ss Score
3.21
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
GAATGGACAGACCAAAAATTACGATGGAATCCCGAAGACTATGGTGGAATTAATTCGATAAAGGTTCCATCGGAGTCGCTCTGGCTGCCTGACATAGTTCTCTTTGAAAA
Seq A exon
TGCTGACGGACGTTTTGAGGGCTCTCTCATGACCAAGGCCATTGTGAAATCCAGCGGAACCGTCAGTTGGACTCCTCCCGCCAGCTACAAAAGTTCCTGTACCATGGATGTCACATTTTTCCCGTTCGATAAGCAGAACTGCTCAATGAAGTTCGGATCCTGGACTTACGATGGTACCATGGTCGACCTCATTCTGATCAATGAAAACGTTGACCGGAAAGACTTTTTTGATAACGGAGAGTGGGAGATACTAAATGCAAAGGGGATGAAGGGCAACAGAAGAGAAGGCTTTTACTCCTATCCGTTTGTTACCTACTCTTTTGTTCTGAGACGCCTGCCCCTGTTTTACACCCTCTTTTTGATAATCCCCTGCCTGGGGCTGTCTTTTCTCACGGTCCTGGTGTTCTACCTACCCTCCGACGAAGGGGAAAAACTCTCCTTATCCACCTCGGTTTTGGTTTCTTTGACAGTGTTTCTTTTAGTAATCGAAGAAATAATCCCGTCTTCTTCAAAAGTCATCCCTCTCATTGGGGAGTACCTCCTCTTCATTATGATATTTGTCACGCTGTCTATTATTGTCACGGTTTTTGTAATTAATGTCCACCACAGATCTTCCTCAACGTACCATCCCATGGCCCCCTGGGTGAAGAGGCTGTTTCTGGAAAAACTCCCGAGATGGCTTTGCATGAAGGACCCCAGGGACCGCTTCTCTTTCCCCGATGGAACGGAGAGTAAGGGAACCGTGAGGGGGAAATTTCCAGGGAAAAAGAAGCAGACTCCTACCAGTGATGGAGAAAGAGTTCTGGTCGCTTTCCTGGAGAAGGCCTCTGAGTCCATCAGATACATCTCGAGGCATGTGAAGAAGGAACACTTCATCAGTCAG
Seq C2 exon
GTTGTTCAAGACTGGAAATTCGTGGCTCAGGTTCTTGACCGCATCTTCCTCTGGCTCTTTCTGACAGCTTCGGTTTTGGGCTCTGTCCTGATTTTTATTCCAGCCTTGAAGATGTGGATACATCGTTTCCATTAGGAACTGCTCTCTGGATCCATGTAGAAGACACACATAGAGAGAATCCCACCTAGAACTGAGGGCTGCTGGTGTGTTCACAGAAAGGAGTTGCATGCAACAGTTGTGGTGCCCTTGCCTTGTCCTGGGAGCCTTCTGTGACTGGAGGAAACTGAGAAAACGTGGGTTTGAGCTAGTGTGATGGTGGCTGCCATTAGAGATGTATTTGGGCAATTCAGAGAAGTCTCCATGTCATGTTGTTGTGTGGGAGGCTCCGAAATGCTCCATTTGCCTATCCCTGAACTACTGCATCTGCCCATCCCCCAGACTTCTACATCTGCTCATCCCTAAACTCTTGATTTTGTCCATCCACTGAACTCCTAGTATCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000031492-'1-7,'1-4,7-7=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.036 C2=0.000
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=FE(17.6=100)
A:
PF0293118=Neur_chan_LBD=PD(55.1=38.3),PF0293211=Neur_chan_memb=WD(100=43.7),PF0293211=Neur_chan_memb=PU(62.1=18.3)
C2:
PF0293211=Neur_chan_memb=PD(35.6=68.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCTGCCTGACATAGTTCTCT
R:
AGCCACCATCACACTAGCTCA
Band lengths:
350-1233
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types