Special

MmuEX6037309 @ mm10

Exon Skipping

Gene
ENSMUSG00000031740 | Mmp2
Description
matrix metallopeptidase 2 [Source:MGI Symbol;Acc:MGI:97009]
Coordinates
chr8:92832764-92836142:+
Coord C1 exon
chr8:92832764-92832892
Coord A exon
chr8:92833069-92833242
Coord C2 exon
chr8:92835969-92836142
Length
174 bp
Sequences
Splice sites
3' ss Seq
AGGCTCTGTGTGTCCTGCAGTGG
3' ss Score
6.92
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
AGCATGGAGATGGATACCCATTTGATGGCAAGGATGGACTCCTGGCACATGCCTTTGCCCCGGGCACTGGTGTTGGGGGAGATTCTCACTTTGATGATGATGAGCTGTGGACCCTGGGAGAAGGACAAG
Seq A exon
TGGTCCGCGTAAAGTATGGGAACGCTGATGGCGAGTACTGCAAGTTCCCCTTCCTGTTCAACGGTCGGGAATACAGCAGCTGTACAGACACTGGTCGCAGTGATGGCTTCCTCTGGTGCTCCACCACATACAACTTTGAGAAGGATGGCAAGTATGGCTTCTGCCCCCATGAAG
Seq C2 exon
CCTTGTTTACCATGGGTGGCAATGCAGATGGACAGCCCTGCAAGTTCCCGTTCCGCTTCCAGGGCACCTCCTACAACAGCTGTACCACCGAGGGCCGCACCGATGGCTACCGCTGGTGTGGCACCACCGAGGACTATGACCGGGATAAGAAGTATGGATTCTGTCCCGAGACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000031740-'9-16,'9-8,11-16=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0041319=Peptidase_M10=FE(13.1=100)

							
A:
PF0041319=Peptidase_M10=FE(17.6=100),PF0004014=fn2=WD(100=71.2)

							
C2:
PF0041319=Peptidase_M10=FE(17.6=100),PF0004014=fn2=WD(100=71.2)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000034187





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr16:55485604-55485777 
HIGH PSI
HsaEX6043812
(MMP2)
Human
(hg19)
chr16:55519516-55519689 
HIGH PSI
HsaEX6043812
(MMP2)
Rat
(rn6)
chr19:15563706-15563879 
HIGH PSI
RnoEX6059789
(Mmp2)
Cow
(bosTau6)
chr18:23834865-23835038 
HIGH PSI
BtaEX6080258
(MMP2)
Chicken
(galGal4)
chr11:3209085-3209258 
HIGH PSI
GgaEX1036599
(MMP2)
Chicken
(galGal3)
chr11:3705380-3705553 
HIGH PSI
GgaEX1036599
(MMP2_CHICK)
Zebrafish
(danRer10)
chr7:35156472-35156645 
HIGH PSI
DreEX6006232
(mmp2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TTGATGGCAAGGATGGACTCC

				
R: 
TATCCCGGTCATAGTCCTCGG

				
Band lengths: 
255-429

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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