Special

MmuEX6041698 @ mm10

Exon Skipping

Gene
Description
granzyme B [Source:MGI Symbol;Acc:MGI:109267]
Coordinates
chr14:56260182-56261234:-
Coord C1 exon
chr14:56261087-56261234
Coord A exon
chr14:56260579-56260714
Coord C2 exon
chr14:56260182-56260442
Length
136 bp
Sequences
Splice sites
3' ss Seq
TACGTCTGCTCTCTTCACAGTAT
3' ss Score
8.77
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
Exon sequences
Seq C1 exon
GGGAGATCATCGGGGGACATGAAGTCAAGCCCCACTCTCGACCCTACATGGCCTTACTTTCGATCAAGGATCAGCAGCCTGAGGCGATATGTGGGGGCTTCCTTATTCGAGAGGACTTTGTGCTGACTGCTGCTCACTGTGAAGGAAG
Seq A exon
TATAATAAATGTCACTTTGGGGGCCCACAACATCAAAGAACAGGAGAAGACCCAGCAAGTCATCCCTATGGTAAAATGCATTCCCCACCCAGACTATAATCCTAAGACATTCTCCAATGACATCATGCTGCTAAAG
Seq C2 exon
CTGAAGAGTAAGGCCAAGAGGACTAGAGCTGTGAGGCCCCTCAACCTGCCCAGGCGCAATGTCAATGTGAAGCCAGGAGATGTGTGCTATGTGGCTGGTTGGGGAAGGATGGCCCCAATGGGCAAATACTCAAACACGCTACAAGAGGTTGAGCTGACAGTACAGAAGGATCGGGAGTGTGAGTCCTACTTTAAAAATCGTTACAACAAAACCAATCAGATATGTGCGGGGGACCCAAAGACCAAACGTGCTTCCTTTCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000015437-'2-4,'2-2,3-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.040 A=0.000 C2=0.138
Domain overlap (PFAM):

C1:
PF0008921=Trypsin=PU(21.4=94.0)
A:
PF0008921=Trypsin=FE(20.5=100)
C2:
PF0008921=Trypsin=FE(39.1=100)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
([1])
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGATCATCGGGGGACATGA
R:
CAACCAGCCACATAGCACACA
Band lengths:
248-384
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types