MmuEX6056610 @ mm10
Exon Skipping
Gene
ENSMUSG00000023034 | Nr4a1
Description
nuclear receptor subfamily 4, group A, member 1 [Source:MGI Symbol;Acc:MGI:1352454]
Coordinates
chr15:101272153-101273193:+
Coord C1 exon
chr15:101272153-101272304
Coord A exon
chr15:101272718-101272920
Coord C2 exon
chr15:101273015-101273193
Length
203 bp
Sequences
Splice sites
3' ss Seq
CTTACCTGCGTTCCTTTCAGTTC
3' ss Score
10.9
5' ss Seq
CCGGTAAGC
5' ss Score
8.8
Exon sequences
Seq C1 exon
TTGTACGGACAGACAGCCTAAAAGGGCGGCGGGGCCGGCTACCTTCAAAACCCAAGCAGCCTCCAGATGCCTCCCCTACCAATCTTCTCACTTCCCTCATCCGGGCACACTTGGACTCCGGGCCTAGCACTGCCAAATTGGACTATTCCAAG
Seq A exon
TTCCAGGAACTGGTGCTGCCCCGCTTCGGGAAGGAAGATGCCGGTGACGTGCAACAATTTTATGACTTGCTCTCTGGTTCCCTGGACGTTATCCGAAAGTGGGCAGAAAAAATCCCTGGCTTCATTGAGCTTTGCCCAGGAGACCAAGACCTGTTGCTAGAGTCTGCCTTCCTGGAACTCTTCATCCTCCGCCTGGCATACCG
Seq C2 exon
ATCTAAACCCGGTGAGGGGAAGCTCATCTTCTGCTCAGGCCTGGTACTACACCAGCTGCAGTGTGCCCGTGGCTTTGGTGATTGGATTGACAACATCCTGGCCTTCTCACGGTCCCTGCACAGCTTGGGTGTTGATGTTCCCGCCTTTGCCTGCCTGTCCGCTCTGGTCCTCATCACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000023034-'14-21,'14-16,17-21=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.353 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0010425=Hormone_recep=PU(32.5=91.2)
C2:
PF0010425=Hormone_recep=FE(31.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGACAGACAGCCTAAAAGGG
R:
AAAGGCGGGAACATCAACACC
Band lengths:
295-498
Functional annotations
There are 1 annotated functions for this event
PMID: 22002310
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, glutathione s tranferase tag, pull down. ELM ID: ELMI002017; ELM sequence: AELSPA; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types