MmuEX6056611 @ mm10
Exon Skipping
Gene
ENSMUSG00000023034 | Nr4a1
Description
nuclear receptor subfamily 4, group A, member 1 [Source:MGI Symbol;Acc:MGI:1352454]
Coordinates
chr15:101271736-101272920:+
Coord C1 exon
chr15:101271736-101271865
Coord A exon
chr15:101272153-101272304
Coord C2 exon
chr15:101272718-101272920
Length
152 bp
Sequences
Splice sites
3' ss Seq
TACTGCCCGTCTCTCTGCAGTTG
3' ss Score
9.8
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
CGCACAGTACAGAAAAGCGCCAAGTACATCTGCCTGGCAAACAAGGATTGCCCTGTGGACAAGAGGCGGCGGAACCGCTGCCAGTTCTGCCGCTTCCAGAAGTGCCTGGCTGTGGGCATGGTGAAGGAAG
Seq A exon
TTGTACGGACAGACAGCCTAAAAGGGCGGCGGGGCCGGCTACCTTCAAAACCCAAGCAGCCTCCAGATGCCTCCCCTACCAATCTTCTCACTTCCCTCATCCGGGCACACTTGGACTCCGGGCCTAGCACTGCCAAATTGGACTATTCCAAG
Seq C2 exon
TTCCAGGAACTGGTGCTGCCCCGCTTCGGGAAGGAAGATGCCGGTGACGTGCAACAATTTTATGACTTGCTCTCTGGTTCCCTGGACGTTATCCGAAAGTGGGCAGAAAAAATCCCTGGCTTCATTGAGCTTTGCCCAGGAGACCAAGACCTGTTGCTAGAGTCTGCCTTCCTGGAACTCTTCATCCTCCGCCTGGCATACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000023034-'15-16,'15-11,16-16
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.353 C2=0.000
Domain overlap (PFAM):
C1:
PF0010513=zf-C4=PD(58.6=93.2)
A:
NO
C2:
PF0010425=Hormone_recep=PU(32.5=91.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATTGCCCTGTGGACAAGAGG
R:
AGCAACAGGTCTTGGTCTCCT
Band lengths:
243-395
Functional annotations
There are 2 annotated functions for this event
PMID: [1]
This event
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis. ELM ID: ELMI000099; ELM sequence: RGRLPSKPK; Overlap: FULL
PMID: 11274386
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis, protein kinase assay. ELM ID: ELMI000100; ELM sequence: RGRLPSKPK; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types