MmuEX6069760 @ mm10
Exon Skipping
Gene
ENSMUSG00000061393 | Acvr2b
Description
activin receptor IIB [Source:MGI Symbol;Acc:MGI:87912]
Coordinates
chr9:119427455-119428568:+
Coord C1 exon
chr9:119427455-119427662
Coord A exon
chr9:119427971-119428076
Coord C2 exon
chr9:119428201-119428568
Length
106 bp
Sequences
Splice sites
3' ss Seq
GACCCTGGGCCCTCAGGCAGGAG
3' ss Score
-1.14
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
GTTCCGGGCGAGGGGAGGCTGAGACTCGGGAGTGCATCTACTACAACGCCAACTGGGAGCTGGAGCGCACCAACCAGAGCGGCCTGGAGCGCTGCGAGGGGGAACAGGACAAGCGGCTGCACTGCTACGCCTCGTGGCGCAACAGCTCGGGCACCATCGAGCTGGTGAAGAAGGGCTGCTGGCTAGATGACTTCAATTGCTACGACAG
Seq A exon
GAGTGTGTGGCCACCGAGGAGAACCCCCAGGTGTACTTCTGCTGCTGCGAAGGCAACTTCTGCAACGAGCGCTTCACCCACTTGCCGGAGCCTGGGGGCCCAGAAG
Seq C2 exon
TCACGTACGAGCCACCCCCGACAGCCCCCACCCTGCTCACGGTGCTGGCCTACTCGCTGCTGCCCATTGGAGGCCTCTCTCTCATCGTCCTGCTGGCCTTCTGGATGTATCGTCATCGGAAGCCTCCCTACGGCCATGTGGACATCCATGAGGTGAGACAGTGCCAGCGTTGGGCAGGGAGAAGGGACGGCTGTGCGGACTCCTTTAAGCCCTTGCCTTTCCAGGACCCGGGGCCTCCGCCCCCATCCCCTCTGGTGGGCCTGAAGCCACTACAGCTGCTGGAGATCAAGGCTCGGGGCCGCTTTGGCTGCGTTTGGAAAGCTCAGCTCATGAACGACTTTGTGGCTGTGAAGATCTTCCCACTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000061393-'7-3,'7-2,8-3
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.088 C2=0.101
Domain overlap (PFAM):
C1:
PF0106418=Activin_recp=PU(65.9=85.7)
A:
PF0106418=Activin_recp=PD(33.0=78.9)
C2:
PF0006920=Pkinase=PU(11.1=26.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCTGCTGGCTAGATGACTTC
R:
GGCAAGGGCTTAAAGGAGTCC
Band lengths:
252-358
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types