MmuEX6073905 @ mm10
Exon Skipping
Gene
ENSMUSG00000027978 | Prss12
Description
protease, serine 12 neurotrypsin (motopsin) [Source:MGI Symbol;Acc:MGI:1100881]
Coordinates
chr3:123486957-123491624:+
Coord C1 exon
chr3:123486957-123487162
Coord A exon
chr3:123489556-123489634
Coord C2 exon
chr3:123491502-123491624
Length
79 bp
Sequences
Splice sites
3' ss Seq
CAACCCCTCTCTGCTTTCAGAGA
3' ss Score
9.85
5' ss Seq
AAGGTAAAA
5' ss Score
8.38
Exon sequences
Seq C1 exon
GGGTCCTGCCAGAGCAAGGACTATGGCTTATTTTGGGGAAGGAAAAGGCCCCATCCACATGGATAATGTGAAGTGCACAGGAAATGAGAAGGCCCTGGCTGACTGTGTCAAACAAGACATTGGAAGGCACAACTGCCGCCACAGTGAGGATGCAGGAGTCATCTGTGACTATTTAGAGAAGAAAGCATCAAGTAGTGGTAATAAAG
Seq A exon
AGATGCTCTCATCTGGATGTGGACTGAGGTTACTGCACCGTCGGCAGAAACGGATCATTGGTGGGAACAATTCTTTAAG
Seq C2 exon
GGGTGCCTGGCCTTGGCAGGCTTCCCTCAGGCTGAGGTCGGCCCATGGAGACGGCAGGCTGCTTTGTGGAGCTACCCTTCTGAGTAGCTGCTGGGTCCTGACAGCTGCACACTGCTTCAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027978-'8-13,'8-12,9-13
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0053013=SRCR=PD(57.1=80.0)
A:
PF0008921=Trypsin=PU(3.3=29.6)
C2:
PF0008921=Trypsin=FE(17.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAGTGAGGATGCAGGAGTCA
R:
TCAGGACCCAGCAGCTACTC
Band lengths:
167-246
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types