Special

MmuEX6077141 @ mm9

Exon Skipping

Gene
ENSMUSG00000015467 | Egfl8
Description
EGF-like domain 8 [Source:MGI Symbol;Acc:MGI:1932094]
Coordinates
chr17:34750954-34752265:-
Coord C1 exon
chr17:34751429-34752265
Coord A exon
chr17:34751115-34751285
Coord C2 exon
chr17:34750954-34751036
Length
171 bp
Sequences
Splice sites
3' ss Seq
CTTCTCTTTCTGGTAACTAGATG
3' ss Score
6.05
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
GCAGACGCTGCTGGTTCCTCTCCGTTACAACGAGTCCTATAGTCAACCGGTGTACAAACCCTACCTGACCTTGTGTGCGGGGAGGCGCATATGTAGCACCTACAGGTGAGAGGTGAAGCCCCTAAGGCTCCCAGGTCTCAAAGGGACCCCAAGAGGCAAGTCCAGGATGGGTACCTACAGATATGAGCCTGCTTCTGTGTTCTAGGACCACATACCGTGTGGCCTGGCGGGAGGTGAGGCGGGAGGTACCACAGACACACGTGGTGTGCTGTCAGGGCTGGAAGAAGCCACACCCAGGAGCTCTCACCTGTGATGGTGAGGAGGCTGGGACTTCAGGCTGTGGGAGGCTTGCTGGGAGCTGGCCCTGTGTCTGGGTCTTAACTGTCTTCTCAAATGGACCCCAGCCATCTGCTCCAAGCCTTGTCTTAATGGAGGTGTCTGCACTGGACCAGACCGGTGCGAGTGTGCCCCAGGCTGGGGAGGAAAGCATTGCCACGTGG
Seq A exon
ATGTCGATGAATGCAGGGCCAGCCTTACCCTCTGCTCTCATGGCTGCCTCAACACACTGGGCAGCTTCTTGTGCAGCTGTCCACACCCCCTGGTGCTGGGTCTCGATGGACGCACCTGTGCAGGGGGGCCTCCAGAGTCCCCGACAAGTGCCAGCATCCTCAGTGTGGCAG
Seq C2 exon
TTCGGGAAGCAGACAGCGAAGAGGAGCGAGCCCTGAGGTGGGAGGTTGCAGAGCTTCGTGGGCGTCTGGAGAAGCTGGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000015467-'7-10,'7-9,8-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.105 C2=0.024
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0000822=EGF=WD(100=81.8),PF0764510=EGF_CA=PU(0.1=0.0)

							
A:
PF0764510=EGF_CA=WD(100=69.0)

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000015611





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000094958, ENSMUSP00000128433
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr6:32167087-32167257 
HIGH PSI
HsaEX7104388
(EGFL8)
Human
(hg19)
chr6:32134864-32135034 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr23:27025540-27025710 
HIGH PSI
BtaEX6098221
(EGFL8)
Chicken
(galGal4)
chr17:7748819-7748983 
HIGH PSI
GgaEX0003046
(EGFL7)
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr21:7681141-7681287 
HIGH PSI
DreEX0029202
(egfl7)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCACCTGTGATGGTGAGGAGG

				
R: 
GAAGCTCTGCAACCTCCCAC

				
Band lengths: 
254-425

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]










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