Special

MmuEX6100734 @ mm10

Exon Skipping

Gene
ENSMUSG00000070953 | Rabepk
Description
Rab9 effector protein with kelch motifs [Source:MGI Symbol;Acc:MGI:2139530]
Coordinates
chr2:34784546-34790655:-
Coord C1 exon
chr2:34790503-34790655
Coord A exon
chr2:34785567-34785728
Coord C2 exon
chr2:34784546-34784695
Length
162 bp
Sequences
Splice sites
3' ss Seq
TTATTTTCTCTCTGGACTAGAAG
3' ss Score
7.13
5' ss Seq
CAAGTATGG
5' ss Score
4.99
Exon sequences
Seq C1 exon
GAACACACCAGTGGGACACGGCCACCAGGGAGGGCCTCTTGCCTCGGTACGAGCATGCCAGCTTCCTTCCCTCCTGCTCTCCTCACAGCATCTGGGTGTTTGGAGGTGCAGACCAGTCAGGAAATCGAAACTGTCTGCAAGTCATGAGTCCTG
Seq A exon
AAGACAGGACGTGGAGCACACCAGAAGTGACTGGCTCCCCTCCATCCCCAAGAACATTCCACACATCGTCCGCAGCTATCGGAAACCAACTATACGTCTTTGGGGGAGGAGAGAGAGGTGCCCAGCCTGTGGAGGACGTGAAGTTGCATGTATTTGACGCAA
Seq C2 exon
ACACTCTGACATGGTCTCAACCGGAGACACATGGAAGTCCTCCGTCTCCTCGGCATGGCCATGTGATGGTGGCAGCGGGCACAAAACTCTTCATCCACGGAGGATTGGCAGGGGACAAGTTCTTTGATGATCTCCATTGCATTGATATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000070953-'9-14,'9-12,15-14
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.340 A=0.436 C2=0.301
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0764610=Kelch_2=PD(20.8=21.2),PF134151=Kelch_3=PU(46.9=44.2)

							
A:
PF0764610=Kelch_2=PD(20.8=20.0),PF134181=Kelch_4=PU(70.4=69.1)

							
C2:
PF134181=Kelch_4=PD(27.8=29.4),PF134181=Kelch_4=PU(68.0=66.7)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000122360





     
                   









    
Main Skipping Isoform:
ENSMUSP00000120887





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000108709, ENSMUSP00000113099
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr9:125220546-125220602 
ALTERNATIVE
HsaEX0051776
(RABEPK)
Human
(hg19)
chr9:127982818-127982979 
ALTERNATIVE
HsaEX0051776
(RABEPK)
Rat
(rn6)
chr3:13852226-13852339 
HIGH PSI
RnoEX0073386
(Rabepk)
Cow
(bosTau6)
chr11:96107928-96108089 
HIGH PSI
BtaEX0029432
(RABEPK)
Chicken
(galGal4)
chr17:9589441-9589602 
HIGH PSI
GgaEX1047816
(RABEPK)
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr5:2461551-2461724 
HIGH PSI
DreEX6008994
(rabepk)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CACCAGGGAGGGCCTCTTG

				
R: 
GAACTTGTCCCCTGCCAATCC

				
Band lengths: 
253-415

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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