Special

MmuEX6100735 @ mm10

Exon Skipping

Gene
ENSMUSG00000070953 | Rabepk
Description
Rab9 effector protein with kelch motifs [Source:MGI Symbol;Acc:MGI:2139530]
Coordinates
chr2:34780597-34785728:-
Coord C1 exon
chr2:34785567-34785728
Coord A exon
chr2:34784546-34784695
Coord C2 exon
chr2:34780597-34780746
Length
150 bp
Sequences
Splice sites
3' ss Seq
TAATGCCTTTACCTTTGTAGACA
3' ss Score
7.24
5' ss Seq
TAGGTAAGC
5' ss Score
8.89
Exon sequences
Seq C1 exon
AAGACAGGACGTGGAGCACACCAGAAGTGACTGGCTCCCCTCCATCCCCAAGAACATTCCACACATCGTCCGCAGCTATCGGAAACCAACTATACGTCTTTGGGGGAGGAGAGAGAGGTGCCCAGCCTGTGGAGGACGTGAAGTTGCATGTATTTGACGCAA
Seq A exon
ACACTCTGACATGGTCTCAACCGGAGACACATGGAAGTCCTCCGTCTCCTCGGCATGGCCATGTGATGGTGGCAGCGGGCACAAAACTCTTCATCCACGGAGGATTGGCAGGGGACAAGTTCTTTGATGATCTCCATTGCATTGATATAG
Seq C2 exon
GTGACATGAGCTGGCAGAAGCTTGGTCCCACCGGGGCTGTTCCAGTCGGCTGTGCTGCCCATGCCGCCGTTGCTGTGGGACACCATGTATATATGTTTGGAGGTATGACAGCCACTGGAGCACTGAACATGATGTACAAGTATCACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000070953-'15-15,'15-14,19-15
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.436 A=0.301 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0764610=Kelch_2=PD(20.8=20.0),PF134181=Kelch_4=PU(70.4=69.1)

							
A:
PF134181=Kelch_4=PD(27.8=29.4),PF134181=Kelch_4=PU(68.0=66.7)

							
C2:
PF134181=Kelch_4=PD(30.0=29.4),PF0134420=Kelch_1=PU(79.1=66.7)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000122360





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000108709, ENSMUSP00000113099
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr9:125227910-125228059 
ALTERNATIVE
HsaEX6063026
(RABEPK)
Human
(hg19)
chr9:127990189-127990338 
HIGH PSI
HsaEX6063026
(RABEPK)
Rat
(rn6)
chr3:13850746-13850895 
HIGH PSI
RnoEX0073387
(Rabepk)
Cow
(bosTau6)
chr11:96111190-96111339 
HIGH PSI
BtaEX6046150
(RABEPK)
Chicken
(galGal4)
chr17:9589952-9590101 
HIGH PSI
GgaEX1047817
(RABEPK)
Chicken
(galGal3)
chr17:10311947-10312096 
HIGH PSI
GgaEX1047817
(RABEPK)
Zebrafish
(danRer10)
chr5:2460442-2460591 
HIGH PSI
DreEX0060377
(rabepk)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCCCTCCATCCCCAAGAACAT

				
R: 
GTGCTCCAGTGGCTGTCATAC

				
Band lengths: 
249-399

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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