MmuEX6101061 @ mm9
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:40678027-40714103:-
Coord C1 exon
chr2:40713922-40714103
Coord A exon
chr2:40707151-40707350
Coord C2 exon
chr2:40678027-40678215
Length
200 bp
Sequences
Splice sites
3' ss Seq
CTATTGATTTTGTTTCCTAGGAA
3' ss Score
9.63
5' ss Seq
AAGGTTGGT
5' ss Score
8.46
Exon sequences
Seq C1 exon
GTAGTGCATAACACTGCTGTCCCCAATGCACTTGCTGTTGATTGGATTGGCAAAAACCTTTATTGGTCTGACACAGAGAAAAGGATAATTGAAGTATCCAAACTCAATGGCTTATACCCTACTGTACTTGTTAGCAAAAGGCTGAAGTTTCCCAGGGACCTGTCTTTAGATCCACGAGCCGG
Seq A exon
GAATTTGTACTGGATTGATTGCTGTGAGTATCCTCACATTGGCCGTGTCGGAATGGATGGAACAAATCAGAGTGTTGTCATAGAAACCAAGATTTCTAGACCTATGGCACTAACAATAGATTATGTCAACCATAGACTCTATTGGGCTGATGAAAATCACATTGAATTTAGCAACATGGATGGATCTCATAGACACAAAG
Seq C2 exon
TCCCTAATCAAGATATTCCAGGGGTGATTGCACTCACTTTGTTTGAAGACTACATCTACTGGACTGATGGGAAAACCAAGTCACTCAGCCGTGTCCATAAAACCTCGGGAGCAGACAGACTTTCACTGATTAACTCATGGCATGCCATCACAGATATCCAGGTGTATCATTCTTATAGACAACCCGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'63-71,'63-70,64-71=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.029 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(33.3=23.0),PF0005812=Ldl_recept_b=WD(100=67.2),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=WD(100=61.8)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAACACTGCTGTCCCCAATGC
R:
GTGAAAGTCTGTCTGCTCCCG
Band lengths:
300-500
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: