MmuEX6101071 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:40715372-40725954:-
Coord C1 exon
chr2:40725848-40725954
Coord A exon
chr2:40725382-40725514
Coord C2 exon
chr2:40715372-40715494
Length
133 bp
Sequences
Splice sites
3' ss Seq
TTCCTTATGTGTTTTAACAGATG
3' ss Score
10.21
5' ss Seq
GAGGTAAGG
5' ss Score
10.28
Exon sequences
Seq C1 exon
CCTTTCCTGTCTGCTCATCAAGTGAATATATGTGTGCCAGTGGAGGATGTCTGTCAGCATCTTTGAAATGTAATGGAGAACCTGACTGTGTTGATGGTTCAGATGAG
Seq A exon
ATGGACTGTGTGATAGAATGTAAGGAAGATCAGTTTCAATGCAAAAATAAAGCATACTGTATACCAATCCGATGGCTGTGCGATGGAATTTATGATTGTGTGGATGGCAGTGATGAAGAGACATGTGGCAGAG
Seq C2 exon
GAGGAAGTATATGCAGAGATGATGAGTTCCTGTGCAATAACTCCCTTTGCAAGCTCCATTTCTGGGTCTGTGATGGAGAAGATGACTGTGGCGACAACTCTGATGAAGCCCCTGACATGTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'104-102,'104-101,105-102=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=PU(89.2=91.7)
A:
PF0005713=Ldl_recept_a=PD(5.4=4.4),PF0005713=Ldl_recept_a=WD(100=84.4)
C2:
PF0005713=Ldl_recept_a=WD(100=92.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTGTCTGCTCATCAAGTGA
R:
CACACATGTCAGGGGCTTCAT
Band lengths:
226-359
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types