MmuEX7000941 @ mm10
Exon Skipping
Gene
ENSMUSG00000075318 | Scn2a
Description
sodium channel, voltage-gated, type II, alpha [Source:MGI Symbol;Acc:MGI:98248]
Coordinates
chr2:65686784-65688814:+
Coord C1 exon
chr2:65686784-65686847
Coord A exon
chr2:65688318-65688459
Coord C2 exon
chr2:65688608-65688814
Length
142 bp
Sequences
Splice sites
3' ss Seq
CCTCTCTAATGTAATTACAGCCA
3' ss Score
4.1
5' ss Seq
CTGGTAAGA
5' ss Score
9.45
Exon sequences
Seq C1 exon
GTCACTTTTATTTTTTGGAAGGACAAAACGATGCTCTGCTTTGTGGTAACAGCTCGGATGCTGG
Seq A exon
CCAGTGTCCGGAAGGATACATCTGTGTGAAGGCTGGGAGAAACCCCAACTATGGCTACACGAGTTTTGACACCTTCAGCTGGGCCTTCTTGTCCTTATTTCGTCTTATGACTCAAGACTTCTGGGAAAACCTTTATCAGCTG
Seq C2 exon
ACCTTGCGTGCTGCTGGGAAAACATATATGATATTTTTCGTGCTTGTGATTTTCTTGGGCTCATTCTACCTAATAAATTTGATCCTGGCTGTGGTGGCCATGGCCTATGAAGAACAGAACCAGGCCACGCTGGAGGAAGCTGAACAGAAGGAGGCAGAGTTTCAGCAGATGCTGGAGCAACTTAAGAAGCAGCAAGAAGAAGCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075318-'6-22,'6-12,17-22=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.043
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(7.8=100)
A:
PF0052026=Ion_trans=FE(17.5=100),PF0253517=Zip=PU(12.6=43.8)
C2:
PF0052026=Ion_trans=PD(11.6=44.9),PF0253517=Zip=FE(40.7=100),PF0043013=ATP-synt_B=PU(79.5=89.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACGATGCTCTGCTTTGTGGT
R:
TGAGCTTCTTCTTGCTGCTTCT
Band lengths:
244-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types