MmuINT0010619 @ mm10
Intron Retention
Gene
ENSMUSG00000052155 | Acvr2a
Description
activin receptor IIA [Source:MGI Symbol;Acc:MGI:102806]
Coordinates
chr2:48896972-48898608:+
Coord C1 exon
chr2:48896972-48897110
Coord A exon
chr2:48897111-48898477
Coord C2 exon
chr2:48898478-48898608
Length
1367 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGG
5' ss Score
9.33
3' ss Seq
CTCCTTCTTTTACATTTCAGGAC
3' ss Score
10.66
Exon sequences
Seq C1 exon
GTTGGTACCCGGAGGTATATGGCTCCAGAGGTGTTGGAGGGTGCTATAAACTTCCAAAGGGACGCATTTCTGAGGATAGATATGTACGCCATGGGATTAGTCCTATGGGAATTGGCTTCTCGTTGCACTGCTGCAGATG
Seq A exon
GTAAGGGAAAAAGCTGTTTTTTTTAAAGTATATGTGCCATATTTATGAAAAGTGGTTATACAAAAAGGTAAGTACATTTTCTTGTATGAACTCCACAAGGTGGCAGAAGATGCAGACAGCAAGGTGAACTTGGAGGGGCTGGGTATGAAATAAACTGGTATTGATACTTTGGAGATGAAGTAGGTTACATAGCACATACTAAAAGAAAATAGATTGCTTAAGAACTTCAGTGTTAGTCCTTCATATCAAACTATGACTCGGTGTGATGGTGACATAGGCCCTGTTGTTAAGTAATACATAGTTAAGGTGATAATATACTACTTTCTGTAGAGTGAACTCTAGAGTGAGGTAAGGGTGAACCATTGGCCCGGACCTGGTAATATAAGGCATTGAAGTAACTATAATGAGGTGCAGTCACAGCTGAGAAATTTAAGGTGTGGTATACAGATCAAGAAGAGTTATTTTGTGGGGAAAGGAGTTATAGGGAAGGGATTCATAGAGCAAGAGACACGGTTAGATGAAGTGTTCAGTGCATCATTATACTTTGCACAAAGCTCATCTATGCATATCTATTTCTCTCTGGTCAATGAAACTGCACAGTAATGACATGTTTGTGTCACAGGGAGCAAAGCACAGACTTCAGATAAGATTTAGATTTCAACTCTACTTCTTAATAATCAGATACCTCTGTATAAAATCTCATAACTTTCTGAGCTATCATATTTACAAAATAGAGCAAATTCCAACTTCATTGGGGGATAAAATAATGCACATTCATGTCTGATATCTAAGAAGAACAAGTTATGTTCCTGAAAAAAATTTGTCATGTGTTACATTTTGACTTGATAGAAATTCTGGTTGACGCACCTTTGTTTTTATAAGTATCATAAATATGTTTTTGAGAGGACAGAAAATTGTAAAGTACATCAGTTACTCAAGTAGGGTGTAGGTGGAGCACTAAGTTTCCAGAGGTGCCAGTGTGCTCCAAATGTTAATATTCTGATATGATATGAATTGATTGCTAAATACCAATAGCTCTTTGTCATAAATAGACATGGGCATTCAGCATATGTATTCTAAAACAGCCTGGTAAGGCTGAATATGAAGATCACGAGTTCAAAGCCAGCCAAACCTTTTAGTCTGGACCTGTCTTCAACAAGCAGCCAATTAAGAACTCATAAAAACAGACCTTTTGTTTTCTCATAAATTGGATTCTGGTTCCACTGTGATACAAGTTCAGCTAGGAGTCCATTTCTTTCCTTTCATTATCTAATAGAGAATGGGAAAAATGGGGCACAAAGTGTGTTTTAACCAGCTTGTACCAGTCAGGAAGCATGTCAGTGGATTCTCCTTCTTTTACATTTCAG
Seq C2 exon
GACCCGTAGATGAGTACATGTTACCATTTGAGGAAGAAATTGGCCAGCATCCATCTCTTGAAGATATGCAGGAAGTTGTTGTGCATAAAAAAAAGAGGCCTGTTTTAAGAGATTATTGGCAGAAACATGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000052155:ENSMUST00000063886:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(16.0=100)
A:
NA
C2:
PF0006920=Pkinase=FE(14.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATATGGCTCCAGAGGTGTTGGA
R:
TGCATGTTTCTGCCAATAATCTCT
Band lengths:
254-1621
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types