MmuINT0011180 @ mm9
Intron Retention
Gene
ENSMUSG00000014852 | Adamts13
Description
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 [Source:MGI Symbol;Acc:MGI:2685556]
Coordinates
chr2:26829449-26831290:+
Coord C1 exon
chr2:26829449-26829518
Coord A exon
chr2:26829519-26831141
Coord C2 exon
chr2:26831142-26831290
Length
1623 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGCT
5' ss Score
6.52
3' ss Seq
CTCTCCCTTCCCCCCCCTAGGCC
3' ss Score
12.53
Exon sequences
Seq C1 exon
AGTCTTCTTCAAGATCTGGAGCCCAAGGATGTGTCTTCTTACTTTGGCCACCATGCTGCTCCATTCACAG
Seq A exon
GTAGCTGTCCTGATGTACTCTGAGCCAGGGGAGTTTCTTGAGCTCTGGATGAGGGACCGAGGGACTTCCCATTGAGTCAGACCCACGAGGGTTCTCTCAGTCATAGAAGGAGGAAGTCAGAGAAGCTAGTCTCTCTCTGTTAATTAGCATCATTGCTTCCTGCCAACTTGATAATAGTTGTTCTGGGTGTTCTGGCTGCCCTGGAGTCCTGACCCCAGGCTTCTGTTCAGCGTCACAAGTGAGGGGATGTTCCTCGGCTGGCCTCCTTAGCCTGTGGATGGCCTCCAGGGGGCTGGCTGATTTTCAGGAACTTGCCACTTCTAGCCATAGCTGTAAATATTTATTCCTTCTTTGGAAACAAGGTGAGTGACAGGCCAAGCAACTCTGGCTCCTGTCCTGTAGTGCTCCTCCTGGAGAAGGCTTTCCCACGACCTATAGCTCTGCCTCTCAGGATTCCATCTCTTTTCTCAGAGGAAAAGTTGGTGGTTTTGATTAGAGCCCTGGTTGGGGGATAGACTGTGGAGCCAGCTCACTTGGTAAAGTGTGTCTGTGTGTGGGAACTTGAGGGCTGAGTTTTAGTTCCTGTGTTCACATAGAAAGCTGGGCAGAGGAGTGCACAATTTCTAATTCCAGTACTGAAGAGAGGCAGTGTGCATTGTTCCAAGACCACAGAAACCTGGTCACAAATCGTATATCTCACAATCCTTTCTATTCTAACCACTGGCCAGGAAAACACACGGGTCGGCCAACCTAGCCTCGTTCCTGAGCCCCAGGTCTCAGTGAGAGATCTTGTCTTAAAAAACAAGATGGGGGACTCCAGAGGAACAACGCCTGAAGTTGACTTCTGGCCTCCATACACACACCATATAGATGCTGACAAGGTCCAGAGAGAGATGAGCCTAGGAGTCAGGGTACAGAAGCTGAGGAGATGTCCCCCCACTTAAACCCAGTTTTTCTGAGGCCTGGGCAGGACACAGTGTCGGGATCATTGGGTCTTCCCACCTCTAGGTTCCTGAAGGTCTGGGACACTGTTCCCTGAGTTCCTGCTCCCTGGGTTCCTTCTCCTTTGAACTCCACAAGACAGTGAGCACTGAGCTGGATTCCTGAGGTCCAGAGACCAAAGCTGGCTATCCTCCTTCCTGTTGGTTCATTTAAGGAACAACCACTTCAAGGCTTAGACTACTTTGCTGAGAACTGATCCAGCCCCTAGGCAAGGTCCAAAGGCTGTAGGCAGCTTGCATTCCATTCTCTCTGGACCCTGGAAGAGCAGGACTCTTATGTAGAACCCTATCTCTGGCCTGTATTCCTCCCTCCCTCTGTCTCACCAAAGAAAGAATACTGGACCTCTCCTCCTTAGCGAGAGGGTCCCAGATGGAGGAGCAGGGGAGAGGGAGGTGGATCCTGTCTCAAGCAGAGCCTCAACTCTTTAAAGACCTGCTCCCTTTACCTGCTTTCCAGCCTGAACTGGGACTCCTGTCCACACCTTCACCAAATACTCAGACTGAGAACTGGGTCCCGAGAGTCGACATGAAATCAGCCTTTTGACTGGTCAGCCCTCTCTGCTAGCTCCAAACACCTGCTTTCTAAAACTTTGGTCCTCAGCCTCTCCCTTCCCCCCCCTAG
Seq C2 exon
GCCATCCTCCCTCTCACCTCCAGAGACTGAGACGGAGAAGGACTTTGGAGGACATTCTGCACCTGGAACTCCTGGTAGCTGTGGGCCCCGATGTTTCCCGGGCTCATCAGGAGGACACAGAACGCTACGTGCTCACTAATCTCAATATC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000014852-Adamts13:NM_001001322:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0142114=Reprolysin=PU(13.5=56.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCTTCTTCAAGATCTGGAGCCC
R:
TTGAGATTAGTGAGCACGTAGC
Band lengths:
214-1837
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: