MmuINT0015022 @ mm10
Intron Retention
Gene
ENSMUSG00000004105 | Angptl2
Description
angiopoietin-like 2 [Source:MGI Symbol;Acc:MGI:1347002]
Coordinates
chr2:33242200-33243949:+
Coord C1 exon
chr2:33242200-33242393
Coord A exon
chr2:33242394-33243678
Coord C2 exon
chr2:33243679-33243949
Length
1285 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
3' ss Seq
TCTCTCTGGATCTTCCCCAGCAA
3' ss Score
6.47
Exon sequences
Seq C1 exon
GTCCATGGAGAGACTGCCTGCAAGCCCTGGAAGATGGTCACAGCACCAGCTCCATCTACCTGGTGAAGCCTGAGAATACCAACCGCCTGATGCAGGTGTGGTGTGACCAGAGACATGACCCTGGAGGTTGGACTGTCATCCAGAGACGCCTGGATGGCTCTGTCAACTTCTTCAGGAACTGGGAGACCTATAAG
Seq A exon
GTGAGACCACTGGGCCTGTATGCATTGCCTGTAAGGTGACTGCACAGCAAGGACAGGACCATCTCTGCAAAGCCATCTGAGTGGTAAGGCCAGGCCTCTCCTTGTCTGCTGTACAGGAGAGGACAGAGAAGAGACAGGATCTTATCCCAGCTGGGGCCTCTGTAAGGTGGCTCTGCTCTTGAGGTCCAGAAGGGGAAGGTGGCAGGGTTCCAGGGCCTGGGAAGCCCCCTAAAAGCCACGCGTAGGGAACTCTGACAATAAGTGGGCCCTAACTACAAGGTCTATTCTCTGGGCCTCCCAGTGCCCAGGATACGGAATGCTTCTCCTTGTAAGTCAAGTGCAAGGGATCTCTCACACCTCCCACCCTGCTCTGAACCAAGAGGGGACAGTAAGGAGGGCATGAGCAGCTCAGGTCAATGGACACATGTCCTGTGTCAGGCACTGTAACTCTTGACTATGCCCTTGAGGGAGGTATTACTACAAAGTCACTTTGCAGGTGAGCAGGGAAAGTACCCTGCACGTGGCTCACAGCTACTGCGCAGTAAAGCAGCAACGGCAGCCGGGGGCTCCCAGCAGCCCCAACGCCTCCAGTCTTCTCCATCCTGGCTTGCCCCATCCGGGTAGCCTGTATATCTCCTGCTTGTCCCTCCTCCAAAGCCTAGCCTTGAGGTCCTCCTTGCACTCCTCCATGTTCTCAAGGTGATGGCACAGCACAGCAAGGGTTCACACATCCTATGGAGGCCGATAGTACCTGGTTCTGAAAACCACTTCAAAGACTTTGGGGGTCACTGCTCACTGATACCCCAAAGCACATATCAAATGAGTAACACAATTACTGAGTTTCAAACCTAGAAGGGCCAGGTGGATGTCACAGGCCTATCACAATTCTTAGCTGTGGCAGTCTATGCTAGAGCTTATGTATAACCCACACACATAACCCATCTCTAGAGAAGGCAACTGAGGCATGGGGGAGGCAATGGCTCTTATCTATGCAATGCTGGCTGCATACCTCCTCGGTGCCAGGCTCTTGAGTGACCACATCTTCCTGCCTTTGAGAAGTTACAGAATCCTCAGGCAATAAGAAATAGGCTCACATGACGGCAGGGAAAAGGTGTGCTCGTCAGATGTGTGAATGGCACATGACTGACAGTTACAAAGGTTCAGTAGCTCACCCAGACATAGAGCCTCATACACAGGTAGCAGGGATTGGAGCCCAGGCCTGCCTTACACTCTGACTATTCCTGGGACACAGACCCCTCACTGAATCTCTCTGGATCTTCCCCAG
Seq C2 exon
CAAGGGTTTGGGAACATCGATGGTGAGTACTGGCTGGGCCTGGAGAACATCTACTGGCTGACGAACCAAGGCAACTACAAACTGCTGGTAACCATGGAGGACTGGTCTGGCCGTAAAGTCTTTGCTGAGTATGCCAGTTTCCGACTGGAGCCAGAAAGCGAGTACTATAAGCTGCGGCTGGGGCGTTATCATGGCAATGCAGGCGACTCCTTTACCTGGCACAACGGCAAACAGTTTACCACCCTGGACAGGGACCATGATGTCTACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000004105:ENSMUST00000004208:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.103 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0014713=Fibrinogen_C=PU(29.3=96.9)
A:
NA
C2:
PF0014713=Fibrinogen_C=FE(41.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGCTCCATCTACCTGGTGA
R:
ATTGCCATGATAACGCCCCAG
Band lengths:
347-1632
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types