Special

MmuINT0015559 @ mm9

Intron Retention

Gene
ENSMUSG00000007827 | Ankrd26
Description
ankyrin repeat domain 26 [Source:MGI Symbol;Acc:MGI:1917887]
Coordinates
chr6:118456394-118457870:-
Coord C1 exon
chr6:118457656-118457870
Coord A exon
chr6:118456623-118457655
Coord C2 exon
chr6:118456394-118456622
Length
1033 bp
Sequences
Splice sites
5' ss Seq
CAAGTAAGT
5' ss Score
10.08
3' ss Seq
GCCCTCTGTGGTCTTCACAGGAC
3' ss Score
9.77
Exon sequences
Seq C1 exon
GCTCAAGCAGCATCCCAGGAGAGCTTGGAGCAGTTAAGAGAGAACAGTAACGCTTCGGTTAGAAGTCAGATGGAGCTCAGGATTAAAGACCTGGAGTCCCAGCTCTACAGAATGAAAGCCCAGGAAGACTTCGATAAAATAGAACTGGAAAAGTATAAGCAGCTCTACCAGGAAGAGTTCAGAGCTAGAAAATCGCTGTCAAGTAAACTAAACAA
Seq A exon
GTAAGTTCTAACATTGAATCTCAGAAAAGAAACTCGGGGCTTTAGCTCTACAGCATCGTCTTCAGTGAGACTAGGAGGCTGTGAGTGCTATAGACAACACTAGAAATAATGTTCATTTGGGATAGCTTATATTCTTTTTTTTTTTATCCTTCTGTCTTAGTTAATATGGTCAACTTTAGGTAGATATTTTTGAAGCTTTATAGTTAAGAAAGTTATATTATTATAAAATTGCTTATTCATGTTCCCTTAAATAGAACTACTAATAGGTTTGATTGTGTTTTGTTTTGTTTTGTTTTGTTTTGGGAAGATGATAACTTGGTCCCAAGGATCAGGTACTGTAATTAATATTCTCCTCTGAGCAATTTCAGCATTTGGTATTTTAATATTCTTTGATTGTCGTCTGTACTGTTTCCAGTAGAGGTCCCTATAAACTGTAATTGACAGGTTTTCTAATCTGTGCTTTTACACGCATGTGCGATGCAGGGAAGCAGTAATGTGAGACTGAAGCTTCAGCACGGCGCCTCTTTCTCTCTCAGCTGTGGCTCTGAGTTATTCCTAGTTTATCCTGAGTAATGGGAGCGAATGCTTACATGTCTCCACTTCTATGTCTTCAGGGAGTGAGATGTGTTAATTATACACAGTGGCACGTCTGCTGTAGTGAAGCAAATTGATACATCAATCATCTCCCAGTTACCACTTAGTGTCTCTGATGAGGCCCTCAGGAAGCCGGGAAGCAGGGCCCTTCCAAGGCACCATGGTTCCTGGTGAAGCTGCTCATCCCAGCAGCCATGTCTCTCCCTCCTACTTGGCTGGAATTTCTCATGTGTTAAGATTCCCTCTAGAAATACCTGCACTTTTTAGAATAATTTTAAACCTGCAATCCTCAGTAGCTGCATTCTGTCAGGTTTTCTAGGCTGTGTCACTGTTGAGTTGCAAATTCCTTGTATTCACCGCAACCTCTTAGACAGCCATGACTCAGGGTTCATTTGGGACCCTGGAGACACTAAGCATTTGCCCTCTGTGGTCTTCACAG
Seq C2 exon
GACCAGTGAGAAGCTGGAGGAGGCCAGCAGCAAGCTGCTCCTGGAGGAGCAGCAGAACAGGTCCTTGCTGAGCACTCTGAGTACAAGGCCTGTTGTGGAGTGTCCTTGTGTTGGAAGTTTCCATAATAGTTTGGTATTCAACAGAACTCTTATTCCAAGAGAAAACATAGTGGTTCCTACTTCAGGCCTACAGCCATCAAATAAGAGAGTGGAGATCTACCTGACCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000007827-Ankrd26:NM_001081112:31
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.194 A=NA C2=0.065
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF120013=DUF3496=PU(46.8=72.2)

							
A:
NA

							
C2:
PF120013=DUF3496=PD(52.3=75.3)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000108449





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000007971
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr10:27013111-27014493 
LOW PSI
HsaINT0008662
(ANKRD26)
Human
(hg19)
chr10:27302040-27303422 
LOW PSI
HsaINT0008662
(ANKRD26)
Rat
(rn6)
chr4:150551041-150552077 
ALTERNATIVE
RnoINT0017764
(Ankrd26)
Cow
(bosTau6)
chr13:17911143-17912373 
LOW PSI
BtaINT0018335
(ANKRD26)
Chicken
(galGal4)
chr1:24106130-24106536 
LOW PSI
GgaINT0109021
([1])
Chicken
(galGal3)
chr1:26132595-26133001 
LOW PSI
GgaINT0109021
([2])
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TGGAGTCCCAGCTCTACAGAA

				
R: 
TGGTCAGGTAGATCTCCACTCT

				
Band lengths: 
351-1384

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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