MmuINT0044657 @ mm9
Intron Retention
Gene
ENSMUSG00000003555 | Cyp17a1
Description
cytochrome P450, family 17, subfamily a, polypeptide 1 [Source:MGI Symbol;Acc:MGI:88586]
Coordinates
chr19:46745447-46747490:-
Coord C1 exon
chr19:46747037-46747490
Coord A exon
chr19:46745583-46747036
Coord C2 exon
chr19:46745447-46745582
Length
1454 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGC
5' ss Score
9.26
3' ss Seq
GCCTTGCCTGCTCTCCAAAGGTG
3' ss Score
9.01
Exon sequences
Seq C1 exon
CAGGCTTGGAGACACTCCAGGATAAACTTCTGCAGGCCAAGAGATAACACGTCTTCAAGGTGACAATCAGAAACGCCTTTTAAAAGTTCTCCTTCTCTGCTGAAATTGCTGTAGCTTCTCCACTCCACAGCTGGCCATCTGCCTACACCTGGCTGCCATGTGGGAACTTGTGGGTCTCTTGCTGCTCATCCTGGCCTATTTCTTTTGGCCCAAGTCAAAGACACCTAATGCCAAGTTCCCCAGGAGCCTTCCATTCCTGCCCCTGGTGGGTAGTCTACCGTTTCTCCCCAGACGTGGTCATATGCATGCCAACTTCTTCAAGCTGCAGGAAAAGTATGGTCCCATCTATTCTCTTCGCCTGGGTACCACAACTGCAGTGATTGTCGGTCACTATCAGCTGGCCAGAGAAGTGCTCGTGAAGAAGGGGAAAGAATTCTCTGGTCGGCCCCAGATG
Seq A exon
GTAAGCAGTGCCAACCCTCCTCTTCCTCGGTCCCTGGGGTTGTACAGTTCTTATTTCTTTCAAAATCAGACTTGTGGGACTGCTCCCTCAAGACCCTACCGAACCTCTAAACTGGGAAGGAGGAATTAACGGGAAAACCCTTGAATGGCTTGTCTAGCAAGATGGTGCAGGGACCTGCAGAGCTGAGAAGCCTGTATGCCACTCACCTTCCCCTCTATGATACGATAATCATTCTAGAATATCCAGGCAAAGCCTTTAGCCCAGACCCAGAGCTAAAGTTCTCTATAAGTGTGACATTGTTGGGAAATAGGGCAGTGATTGCATCCTCCACCAGAAGATGCTTGGAGAAGCGGCTGGCATCATGGAGGGCTAGGACTGCAGTTTCTCTTATATGGCTTTGGCTCACAGATAGCTGGGGGAATATTACAGGGGGAGAGGGGACAAGGGACAGGGACATACAGTAGTATCTTGGGGCATCTGTTCTCATTTGTGCTGACTGTTGAGTAGCCATCCTACAAACACCACCTGTGCTCCCATGACCCTGTTGCAAGTGTTCCCCTGGGTACCCCGATAGAGGACGACCAGCCTCAGCTTTTAACAGGCCAAAACAAATTCCTTTTCCATGCGCTGGTCAGCCAGCGTGGCTGCCCAACTGCCAGGCTCTCTCAGGTTTGGGTTCCTCTCAGAAGCAAAGGAATAAACTGGGCCAGGTGACGGCAGCACACGCCTTTAAGGCTAGCACTTGGGAGGCAGAGGCAGAGGCAGGTAAATCTCTGGGTTTGAGGGCAGCCTGGTCTTGCCAATGCTATACGGGGAGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGGAATAAAACCATCACCACCACCCTGTGAATAAGAGACTAGCCTGGTGGGTTTTGGGGAGAGTCGGGGATGGAGAATGAAGACTTAGACCCTTGTGTTTTGTAGATGGCATCTTTTAGAGATGATAGCTCAAGCTTAAGTCCAACCTGGGAGGATCAAACATCTGCTGTCTCCAAATGAGGATCTGAGGCTGGGTGCACAGGCCAGCAAGTATGGCTTTAGCAGCCTGGTGGTTGGGGACAAAAATAGAGCTGTCTTGGAAGTCTCTCAGTCTCCTCGTCCCTAGGACAGACTCACCTAGCTCATCCCACCCATAGCTGACTCTCCAGGTCAAAAATTGAACTAGAGAGTCCCAGAGGGCACCCTACTAATGACCTGAACCCCAGGGCTCTTGCATTCAAATCCAGGGTTCTTTCTGTCTCCTCGCTCTACTGCCTTTCATGGAACTTTAGTGAGGACTTTGGGGCGTCCTACTAAGTAAGAGAGGCATAGGGATCTCACAGCACTCATCAGGACTGCAGATAGATAGATGGAGAAGCCTGAGAGTTCCGGGAGTTTGCCTGATAATGCCTACAGCCTTGCCTGCTCTCCAAAG
Seq C2 exon
GTGACTCTAGGCCTCTTGTCGGACCAAGGAAAAGGCGTCGCCTTTGCGGATAGTAGTAGCTCCTGGCAGCTGCACCGGAAGCTGGTATTCAGCACCTTTTCCCTGTTCAGGGATGACCAGAAACTGGAGAAGATGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000003555-Cyp17a1:NM_007809:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=PU(15.3=71.7)
A:
NA
C2:
PF0006717=p450=FE(9.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGGTCTCTTGCTGCTCATC
R:
CAGCTGCCAGGAGCTACTACT
Band lengths:
357-1811
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: