MmuINT0050316 @ mm10
Intron Retention
Gene
ENSMUSG00000030409 | Dmpk
Description
dystrophia myotonica-protein kinase [Source:MGI Symbol;Acc:MGI:94906]
Coordinates
chr7:19083849-19086077:+
Coord C1 exon
chr7:19083849-19084154
Coord A exon
chr7:19084155-19085985
Coord C2 exon
chr7:19085986-19086077
Length
1831 bp
Sequences
Splice sites
5' ss Seq
GGGGTGAGT
5' ss Score
7.93
3' ss Seq
CTTCCCCCACCCCCGCCCAGTGG
3' ss Score
5.99
Exon sequences
Seq C1 exon
GAACTGGCCAGAGAGACCCAAGGGATAGTCAGGGACGGGCAGACATGCAGCTAGGGTTCTGGGGCCTGGACAGGGGCAGCCAGGCCCTGTGACGGGAAGACCCCGAGCTCCGGCCCGGGGAGGGGCCATGGTGTTGCCTGCCCAACATGTCAGCCGAAGTGCGGCTGAGGCAGCTCCAGCAGCTGGTGCTGGACCCAGGCTTCCTGGGACTGGAGCCCCTGCTCGACCTTCTCCTGGGCGTCCACCAGGAGCTGGGTGCCTCTCACCTAGCCCAGGACAAGTATGTGGCCGACTTCTTGCAGTGGG
Seq A exon
GTGAGTATGGATAGGAAGCCTGGGGTTGGGTGCAAGGCAGAGGTGGGTCTACAGGGCAAGAATGGGCTATGGAGGGGCAGGAGGGCCTGGAAAGGGCTTTTTGTAAGGGAGCCAAGCAGAGCTCATGACCTGACCCCAAGCTCCCCTGGTGAGGCACCAGGGTCAGTGAGGCCACCTATGACTCAGCCAGTGCAGGCTGGGGTGGGCATAGCCTCCTGCTATCTCAGCACCCACACTAGGACCTGGCAGCTTTCTCTTTTAGGACCCTTGGCTCCTCAAACTGGCTTCATAGCCCTCCCCAGTTTCCCAGAGTGTGGGGAGGGACAGCGTGGGGCAGCTGCCAGGGTGTGGCCCATAGGCAGGTGTTTGGCGTCTGCCTCCCCAGCTGCCCTGACAGGTGTCCAGGAGCTATGAGGGCACTGTGACTCACAGAGGCCCTGGGGGAGAACCAGCCCGGCAGACAGGCGCCACCGAGCACCCTTTCTGTTCCCCAAATTAAGAGGAAGGAACAACTTCAGCTTCTGAGTGTGCCCATCCCTAGCACTCTGATCCCGCCCAGCCTTTGTGGGCCAGATTGGTCATCCCTCCTGGCTTCTCATCTGCTTTTGTGGTTCTAGCTCAAGACCTCTAATTCCTCTGCTGACTTAAATGCCCTTCCCCAGAGGTCTTCTCAGGCCTAGTGGACAAGCTTGGAGCCTTATCTGCTCCTGCCCAACATTGAGCCAAAGCTCCAGCTTACCCCAGCTTCCTTACAAGTAACGACCTGTTTTGTTGCTCTGTGCCTATTATTAAGGGTCCAGGTCTTGATTCTTGGCTGTCTGCCCATGTGTGTGACCCTAGTGCATTCTCCCCTCCTCCCCCGTTTCACAGATGGAAAGGTTGAGGCCATCGGTTAGACTGCTAAGCCTGTGAAAGACTTTTTCTCCTCTCCAGTCTTTAGTGTCTCCCTCAACCTTTCTTTTGAAGGATGGGGTTTGGGCTGGCAGGGTAAACTGAGAACTGGGGTGGGGGCAGGGGGTCTGACCCTCTGGGAAGGAGCAGTCCTTTTGTGGCCTGAGCAGCATCCTGTGGGCCCCTCCCCTGCCAGGCCTGGGCGGGGGAGGGGGCCTGGGTTCCCGCTGCCTTAAAAGGGCTCAACGCCTTGGCTCTCTCCTCCTCCCCACCCCCCAGCCTTGGCCCTAGCTGTATCTTCCCCGGCTGCCCACTTTCCCAAACCCCTTTCTTCTCTGTGACCCCATCTCCCCGCTTCCCCACACGTCCCTCCTCCATCCTTACTCCCCGGCCTTAGAACTTCCCTAAGGGAGATCTGACCTCCCTCTGCCCACCCCGCACCCCCAGTCGCCAGCCTCAGACCTAGCTGCTCTCCCCTCTGGCTGAACCACCCTAGCACAGGACCTTATACCCTGGAGCTTTGGTTATAAGAAGACTCTCCTTCACCCTTTGGAAACCAAGAAAGCCCTTCCAACAGTGTCCAGGATGCTGGAGGGCAGTGACCCTCCCCCACTTCTTCTTCGTGCTGGCTGTGCTGACACAGCTCCAGTTCGAGGTTGTGGCCCGAGACATTAAGTGAGAGCCCCGGGTGACCTGACTTAGCACCCTGATCATCACATGGGAGTGAAAGGCCTGATGCGCCAGCTTCTCCCACTGCCTCCCTTTCTGCCCTGCAACCCTGTGGAAACAGGCAGTTCTGGGTCCCACAAACATCACAGAGGTTTTGAAAGCAGAATCCTAAAGCCGATTTAAGGGGCAGAAGGAAGGAGGCTATAAAGTCACTACCCTTACCGCTAGTGTTCTGATGACCCTTGGTTCTTCTTCCCCCACCCCCGCCCAG
Seq C2 exon
TGGAGCCCATTGCAGCAAGGCTTAAGGAGGTCCGACTGCAGAGGGATGATTTTGAGATTTTGAAGGTGATCGGGCGTGGGGCGTTCAGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030409:ENSMUST00000032568:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0006920=Pkinase=PU(4.8=41.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCAGAGAGACCCAAGGGATA
R:
AATCATCCCTCTGCAGTCGGA
Band lengths:
351-2182
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types