Special

MmuINT0050521 @ mm9

Intron Retention

Gene
ENSMUSG00000019027 | Dnahc1
Description
dynein, axonemal, heavy chain 1 [Source:MGI Symbol;Acc:MGI:107721]
Coordinates
chr14:32100898-32103761:-
Coord C1 exon
chr14:32103607-32103761
Coord A exon
chr14:32101076-32103606
Coord C2 exon
chr14:32100898-32101075
Length
2531 bp
Sequences
Splice sites
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
3' ss Seq
CTCCTCCCTGGTGGTTACAGGAC
3' ss Score
7.29
Exon sequences
Seq C1 exon
TGTTACAGAGTCCTGGCAGCCGCCATGACATTGCTGAAAGGGAAGCCATCCATCAGTGGTGGCGTGTATGAAGCTGTCAACTACTACGTGCTCAACCCCAAGTCCATCACGATGGGCCAGCTGTATGGGGAGTTTGACCTGCTCACCCATGAGTG
Seq A exon
GTGAGTGAGCCCCAAGCTGCTCCCAGTGATGTGCTCCCAGGCTGCCTGCAGTGGCAGAGAGGAGTTTATGCTCTCAGCAGAAAGCCTAGGATGATACGCACCATCCTACTTCATCCCTTAGCGACTTTCCTCAGTTCTGACATTGGCACAGTGACGACAATAATGGCAGGGTTATAGTGGCAAGGAAAGGGACTTGACACATGAAATGCACTGGGGAACAATGGCTGGTGTGGATGAACACTCAGCAGATGGCTGTCTTTACCCTGAGAGAAGCTGAAGAGGTCACTTCCAGGCCTCGCTCCCAGGCTAGGCATGTATTTTAGGGAGATGCATGCATCTGGAGAAGGGCAGCTGAGGGGAAGCAGCCTTGAATGTTACAACCCAGGGCTCCTAAGATGCAACAACAACACAAAAAGCAAAAACCCCTGAGCATCTTCTCCGGTCTTCCATCTCCTGCTGGAAATGTGTGCTTAGCTGTGGTGCCCTGTGAGCCAGTAAGGGCTGGCCACCAATGAGGGCAGACTCACCTTCCTTTCCAAGTTTGGCTGCTTGGTCTTCCCATTTCTGTTTAATGGTCTTTCCCATGTCCACTAGAGACTCATGTGAGTGGTGGTGGGGTTCATAGGTCAGCCCAGGAAAATGTCCCATTGAAGAAAAATATCTAACTGTATCTCAAAGCATGCTAAAGAAGACTTTATTTGGGACCATGACCACAAACATAGAAACTACCTGGGCATGGTCTCAAGATCGAGGACAGAATGAACTCAACTCCAAACACAGCAAGGGCCAATGGTGCATGGTAAACACCAGTGGATAGAGAATTCCTAAGAGGGTAACATCAGGAGTAAGGGTGTTTGTGGCTAAACTGACTTCACAAGGGCCAAGTGGTCAGACCTCAACTGCAGGAGGAGGAGAGTGGGGTCCTGAACAGGTGTTGTGGTGGGTAAGTGTGCGAGGTGAGGACTTGTCCAAACTGACTTGGCAGGGTTGGTTGCCAAGGAGACTCAGGAACCAAGCAGAGAATCTTTCCCTGGCATAGAAAGCTGGTGAAAACTGAGCCTTTCTTAGGTTATGAAGCAGAAATGTCCCTTCTCCAGTTCCTCCCACCTCCCCTCCCCCTTCTTCCTCCCACTGGGACACCACCATTCACCTTTATGCACAGGGACTTCCGTGGGAACTCAGCAGGGAGTCCCATTATATGTTACACCGAGAGCTCCAATTTTTCCCATTAAAATGTTTTAATGAGTGAAGATATGAAGAGTTAAGAACATGAGAACCAGTGATCGCAGTACGTTGTATGTAAGTAATACACTAGCCAAAACAGGTCATAGATTTGGAAATACATTTGTATCTATATGTGACCTTAGAGTTTTATTCAAAATACAGTAGAACCCTGGCTGTCCCCATCCTACCCCATCAGACAGTTCATTTCTGTATCCATTTGCCTGAGGTCAATCTGTAAATATTAAATGAAAGTCCCAGATAAGCAGAACTTATGCATTTTTAAATTGTACATTCTGAACAGTGAGAAGAAATCCTGTACTGATCCATCCCATCCCACGATTGGGATCCCATCCCACAGTTGCCCAGTGTGTTCATGGTCTTTGTCTCTCCATTAGCCCCTATTAGCCGTGTCAGTTACCAGACTGACTCATGGTCTCATTGCTTGTGTTAAACAACTCCTCGTTTAACCAACTATGGCTCCACAGTGTAAACTTTTATTATAGTATCCTACTATAATACATCCGGAGAAGATGTTCAGGGGTTTTTGCTTTTTGTGTTGTTGTTGCCTCTTAGGAGCCCTGGGTTGTAACATTCAAGGCTGCTTCCCCTCAGCTGCCCTTCTCCAGATGCATGCATCTCCCTAAAATACAGGACTATAGTGTCCTGTCTATTAATATATCTAATTATAAATCAACTTTCTCATACGTATTTATATATAGAATAAACCAGCTTATATAGAGGATTCTGCACTATGCACAGTTTCAGATATCCACAATGGGGATGCAGGTGGGGAATCTTAGAATGTTTCTTTGAAGATAAATCAATGTTTTGGGTTTTTTGTTTTTTGGTTTTTGTTTGTTTGTTTGTTTTTTGTTTGTTTTTTGTTTTTCGAGACAGGGTTTCTCTGTATAGCCCTGACTGTCCTGGAACTCACTTTGTAGACCAGCCTGACCTCGAACTCAGAAATCTGCCTGCCTCTACCTCCAGAGAGCTGAGATTAAAGGCGTGCGCTACCATGCCCGGCGTAAATCAATGTTTTTAAGTAAGAAACCAGTTTCTCTCTCTCTTTCTCTCTTTTTAAAATTGACCAATACTTCTGTATCTGTTTGGTAACCACTCAAAAACTGAATTATATCAGTGTATGAAGACAATATGATGAAACCCATGGTTAAACATAATTAACATGTGCTAATAAAAAAATGTTAAAAGATGAGAGCCAGCTGGGTAACTAGGCTTCGCTGGGGACCATTTGTGCCATCACCCGCCTCCCTGGCACCTACATCCCTTCTCCTCCCTGGTGGTTACAG
Seq C2 exon
GACAGATGGAATTTTCTCCTCCCTCATCCGGGCCGGGGCCATCGCATCTGACACCAACAAGAAATGGTACATGTTCGACGGGCCGGTGGATGCCGTCTGGATAGAGAACATGAACACCGTGCTGGATGACAATAAGAAGCTGTGCCTCAGCTCTGGGGAGATCATCAAACTCACAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000019027-Dnahc1:NM_001033668:36
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF077289=AAA_5=FE(34.7=100)

							
A:
NA

							
C2:
PF077289=AAA_5=FE(40.1=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000043281





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000132331
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr3:52366888-52368740 
ALTERNATIVE
HsaINT0049166
(DNAH1)
Human
(hg19)
chr3:52400904-52402756 
ALTERNATIVE
HsaINT0049166
(DNAH1)
Rat
(rn6)
chr16:7372257-7374542 
LOW PSI
RnoINT0048589
(Dnah1)
Cow
(bosTau6)
chr22:49068139-49069397 
LOW PSI
BtaINT0050109
(DNAH1)
Chicken
(galGal4)
chr12:3069612-3071224 
LOW PSI
GgaINT0019480
(DNAH1)
Chicken
(galGal3)
chr12:2895901-2897513 
LOW PSI
GgaINT0019480
(DNAH1)
Zebrafish
(danRer10)
chr11:34420086-34420605 
LOW PSI
DreINT0057985
(dnah1)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"