Special

MmuINT0050710 @ mm9

Intron Retention

Gene
ENSMUSG00000018581 | Dnahc11
Description
dynein, axonemal, heavy chain 11 [Source:MGI Symbol;Acc:MGI:1100864]
Coordinates
chr12:119166792-119169771:-
Coord C1 exon
chr12:119169607-119169771
Coord A exon
chr12:119166933-119169606
Coord C2 exon
chr12:119166792-119166932
Length
2674 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
3' ss Seq
GTCGCTTGATCCCATTACAGGTG
3' ss Score
6.92
Exon sequences
Seq C1 exon
CTGGTTTTGACCAAGCAGCAAAATGACTTTAAGATAGAGCTGAGGCAGCTTGAAGACGACCTTCTCCTGCGCCTCTCTGCTGCTGAGGGGAGCTTCCTGGATGACACAGACCTGGTAGAGCGCCTCGAGACGACCAAGGCCACTGCAGCAGAAATAGAGCACAAG
Seq A exon
GTAAGAGCAGCAGAGAACCCTGGGCAGGCTCAGTACTCTGCTGAAATGGAACAGATGACAGCTGTCAGCACAAAACACAGCTCTCTCCATTCAAAGGAAGTAAGAGTTTATTCTAGAGCCAGTTATGGGTGACTATGGCCTAGGGACGCAGATTCAGGTTACCCCGAAGACTGTGTTTTTATAGTAACAGATAAAAAGAAAAAAATTAACCAAGGCACTTGCATTAGGTAGGTGGGTTATAGCAAAATAGGGAAGCTACTATAGGTCTCAGAAGCTACATAGGCGTCTTCTCAGTTTTGAAGCTTGTAGAAGCTAGTGGCTTACTAAGCGTCATTTTAAAAGTGTTTATGATCTATTTATTTTTATTTTATGCAATTAGTGGTTTGCCTATCTGTGTGAGGGTAGCAGATTCCCTGGAGTTACAAACAGTTGTGAACTACCGTGTGGGTGCTGGGAATTGAACCCAGGTCCTCTAGAAGGGGAGCCAGTGATCTTAACTGCTAGCTAGCTCTCCAGCCCCCTTTTAAAGGTTTTTGATAGTCACAAGTTCAGACATGGATATGTAGCCCATGAGTGGCTTTCAAGGTACTAAAAATAATGAAAGATAATTTGGCTCAGGTATGAAACATTTTAACTCTGCACAAACAGGAAGTTCTATCCTTGGGGAATGTTACTATGAGTATAACTTTTAACACCACACCCTCTAGGAATTTCAGTTCACACAATGTAATCAGAGTCTGGTGCCTCCTCTAGGAAGACAGGTTTGTTGTATAACTTAGGACACTTAATAAACATTCCTCAATCCTTGGGCTACCAGTACGGGATTAAGAGCAGAAATAGTTCTATTTGTACTTCAAGTTCCATAGCGATGCAGTCATTCAATTATATTAATATTTCTTGTGTGACCAATGTTGGAGCCTGCTGGTTTACATGGTAGAAACTAGAGGAGGGGCAAAGCTCAGCTCCAAGGAATAGTATCCCAGTGGATTGTGTTTTTAGAGATGCCTTTGGAGCTGAAGTTTTATTTCCAGACCTCTGGTAGCAAGAAACCAAGCAGGGAATGATCCCATGTGGGTCTCAGTGCACCATCTACCCTGGAAAAGTGACATTTCTCAAAAGCCAATAAATCATTTCCCATGAACAGCTTCCTTGTAAGTGAGCAGCATAGATCACAGTGGGCTGTGTGTGCACTTTGGACTTTCACAAGTGGCCGCTAGCTGTTAACATTGCAGAGTTTGGATGGGAATTAGACTCGTACTTTTTGTGGCATATCCTCCTTTCTAAGTAATCCAGTAATTACCCAGCAGAAGCTATGTCGCCATACACCCAATGTATGTGCCTTAAATTAAGCAAGGCGATAGAATACCAAATTACTCTCTCAAGTAAGTGTTTTCTAGGTGGCTCCTAAGATAGTAAAGATTAGAGCAATTAAGTAAATTAAGGCTTTGAGTTAACTTCCTGTCTTCTTAATGTATCACCATGAAGTCACAGCCCTCTCTGCCTTGTATGTCATTCACATACATCATGAGCCAAGACCATAGCAACGTTCAGGGGGGAATATTGTATCGCTTAAAGCTTCAGTGGGCCAGCAGCTTGTATTCTTAGAGAAAAAAAGAATAGGTTTGTATTTGGCTTTAGAAATTGGTATTTTTTTTTTACCCTTAAATAAAAATGATTAATTGATGGTGATATATCTCATCTCAGAAAATGTGTCCGGAAGCTAACAAGTAAGAATAAGTGGGAATGTTTGAGTGTATGGAGAGCTGGTGCTGTTGTAATTTGATGGCTGGGGGAGCCCTGATACAGAGGCTGTTTAGGAAGCGCTTGGCTATTGCAGGTGCTATTGACCTTGGCTGCATTTGTGGATCTCATTGTTACCTAATAAAATCATTGACACTGAGTTGACCCAGCAGACTTTTAAGAGCCATCCCTGGGAGGTGATATAGCTGGATTGTTAAGGCCTGAGCGAGAGAAGGGAGGCAGGAAGGTGACATCACTCAAAAGCAGATTCCACAGAGGCAAAATAATTAAGGTCATTTAAGTCTACAGGGTGGGATGCAGCTAGTGCCCTCTGCTTTCCTGGTGGAATGCAGCTCATGAAAAAAAAAAAAAAAGGTTACTTGAAAATAGGTATTTAAGAGTTTCTTTAAATTTTGATATTTATTATTTGGATACATATGCATGTGTGATATGCACACATCAGTGTGGGCTCCCATGTACCACACTGTACATGGAGGTCAGAGGACGACACTCCAGAATTGGTTTTCTACTCCCACCCTGAGATTCCAGGTTCTAACTTAGGTCACGGGACTTGTGTGGCAAGCATCTCACTGGTATGGACTTAATAATTTCATCAAACCTCAGGTCCACAGATGTCAGGCCTGTCATGGACTTGCCTTCCTTTGCTTGCTTTGATTTACTGAGTCGGGGTCTCAGTCTCTACTGCAGGTTGTTCTTAAGTTGAACACATTGTGGTATTGCGGACCAGACTCAAACTTACAGCAGTGCTCCAGGTTCAGCCTTCCAACTACTACTGGGAATAGAAACATGACCACAGCATCGGGGTCAACTAGTAATAGTTGTTAATTTCAGATATTCCCGAGAGTCCTTCCATTGCTGGAATTGTTTAGAAAACACAAAGATAAGTTACTGCTGTCGCTTGATCCCATTACAG
Seq C2 exon
GTGACAGAAGCCAGAGAAAATGAAAGAAAAATCAATGAGACCCGTGAGTGCTACAGACCAGTGGCAGCGAGAGCATCCCTTCTGTACTTTGTCATCAGTGACCTCAGGAGAATCAACCCCGTCTACCAGTTCTCTCTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000018581-Dnahc11:NM_010060:67
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.055 A=NA C2=0.149
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127812=AAA_9=PD(22.8=94.5)

							
A:
NA

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000081867





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr7:21852632-21854314 
LOW PSI
HsaINT0049354
(DNAH11)
Human
(hg19)
chr7:21892250-21893932 
LOW PSI
HsaINT0049354
(DNAH11)
Rat
(rn6)
chr6:145829639-145832342 
LOW PSI
RnoINT0048701
(Dnah11)
Cow
(bosTau6)
chr4:30742895-30746118 
LOW PSI
BtaINT0050296
(DNAH11)
Chicken
(galGal4)
chr18:1145345-1147558 
LOW PSI
GgaINT0127387
(DNAH9)
Chicken
(galGal3)
chr18:1128770-1130983 
LOW PSI
GgaINT0127387
(DNAH9)
Zebrafish
(danRer10)
chr16:19404731-19404961 
LOW PSI
DreINT0009170
(DNAH11)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"