HsaINT0049354 @ hg38
Intron Retention
Gene
ENSG00000105877 | DNAH11
Description
dynein axonemal heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:2942]
Coordinates
chr7:21852467-21854455:+
Coord C1 exon
chr7:21852467-21852631
Coord A exon
chr7:21852632-21854314
Coord C2 exon
chr7:21854315-21854455
Length
1683 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGGA
5' ss Score
9.45
3' ss Seq
TTTGTTTGATCCCACCATAGGTG
3' ss Score
7.7
Exon sequences
Seq C1 exon
TTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCCTTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACAAG
Seq A exon
GTAGGAAGGGCAGAGGGTGCCTGGCAGATTCTAATGCTCTGTTCGAATGAGACATGTGGGGTGGGCAGTGTGATCAGACTTGGTAATTCCTCTAAGAGGACCAGCGTGTGGAATTCAGGTGATTTAATAAGCTGCAGTTGGACTGTGTGGGATTGTAAATGGAGATGGAGATGGTTGAATGTGTGCTTCTCCTAATTCCATAGAGATGTCATTCAAATTAGACACTGTCCGGCTATTATTTTTCCTGGGTGACCAAATGTGAAGAAAAGCTGAGGCCTGCTGGCTTCTATGGCTGAAAATCTGAAAAGCCTTAGCATCCGGCTCTTCCAAACTCATATCCTACAGTTTCTCTGCAGGTTCTCCAAGCTGTTGGACATTTTAAAGAAATTCTTAGAGTGAAAGTTTTGTTTACAGGCCTGCCGTGGCAGGATACCGAGCAAAGGATAATCTCCTGCTGTACTCAAATGCACTATTCACCCCAGGAAAAATGACATTTCCTAAAAGCCAGTAGAAATTTTTATTAAATAGGCTTCCTGCTAATGTCCAACATGGGTCCCAATATGCCTTATGTGTGATGTGCACTTTGGACTTTCACAGATGACCGTTAACCCTTAAAATGCCATTGTTTCAGTGTGAATTAGACCCTTATTTGCTTTCTGGAATATCCTTATTACTAAGTAATCTATTAATTACCCAGCAGAAGCTGTGTCACTACGCATCCTTTATATTTGTCTTAAATTAAGCGAGGAAATGGAATCCCAAATTACTCTGTCTTTTCAAGTAAGTGAATATTAGGTGGCTCCTAAGATGGTAAAGTTAGAACAATTAAGTAAATTAACTTAGCTTTGAAGTTAACTTCTAATTGTCTCTTAAAATGTGTCTTCCTATCTTCTTAATATATCACCATGTAGTGACTTCCTTCTCTGCCCTACATTTTATTTCCTTTTATACACAAATATTATGAGTCAACTCTATAGAGAAGGTTGGGGAAAATACTGTATCCTATGGGACCAGCAGTAGTCCTAGATAAAAGAAATAGATATTTGAGCCTTGGGTAAAACTGATATGTTGGTTGATGGTGGTGCTGGTTTTTCTTTTTAAATTATCTCTCTGAATGTACCCAGAGGCTAATACATAAAGATAAACTAAATGGAAATATATGGACATATGGATGATCCAGTGCAAAGTTAGAATTAGGCATGAGAGTCTCTATATTAAGGCTTTTTAGTAAGCATAAGTTACTGGGTATATTATTGACCTTGACTGCTTTTGTATGCTTTGTTGCCTAATGAAGTTATTGGCATTGAATTGACCCAGCAGACTTTTAAGAGCCATCCCTGGGAGGTGATATAGCTGGGTTATTAAGCCTTGAAAGAGAGAGGGGAGGCAGGAAGGTGACATTACTCAAATTCTGTAGAACAGAAAACAACTAGGTTTGTTTAATCTGTAACCTAGAAAACCGCTAGAGTTATGTCCATTCTCACTGAAACTCAGTTTATTAAAAAAATTATTTTAAAATATGAATGTAATCATTTTAGAAAAGCTCGAGCACATGGATGCCATGCATGTTATCTATTTTAATACTCATAATTTTTCATTTCAGGTACGTCCTTCCATTCCTTGGATATGCGTAGAGAATATGAAGAGTAAATAAGTTACTTATTTTGTTTGATCCCACCATAG
Seq C2 exon
GTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATTTTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105877:ENST00000409508:67
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127812=AAA_9=PD(22.8=94.5)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGTATTGACAAAGCACCAAAATGA
R:
TCAAAGAGAATTGGTAGAGGGGGT
Band lengths:
303-1986
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development