MmuINT0062973 @ mm9
Intron Retention
Gene
ENSMUSG00000024598 | Fbn2
Description
fibrillin 2 [Source:MGI Symbol;Acc:MGI:95490]
Coordinates
chr18:58185986-58187596:-
Coord C1 exon
chr18:58187471-58187596
Coord A exon
chr18:58186193-58187470
Coord C2 exon
chr18:58185986-58186192
Length
1278 bp
Sequences
Splice sites
5' ss Seq
TCGGTAAGT
5' ss Score
11.78
3' ss Seq
CATCTTGTGTTCCGCTCCAGACA
3' ss Score
7.94
Exon sequences
Seq C1 exon
ATGAGAACGAATGCAGGACTAAGCCAGGCATCTGTGAAAATGGACGCTGCGTTAACATCATTGGGAGCTACAGGTGTGAGTGCAATGAGGGATTCCAGTCGAGTTCCTCCGGCACTGAATGCCTCG
Seq A exon
GTAAGTGAACACATGACTATTTCCCTGGGTGAGTATAGCACGTCTATGACGTCATCGCAGAACAGCTCGGCGCATTCACCCTTGTCTATTGAACAGACCTTGTACAAGGCCAGTACTCCACACGCCCCGCCCCCGCCCACAGATACCCATCTATTAAAATGATGTATCTCTATGCCTACGCCTTACACGCCCATGTAACAACCTGAAACAGTCTTTCCAAAGGGGAGATTAGTTAAGCTCTGTGGAAAATGTGACTTCAGTAAGGCTGACATCAGGAGCTGATTTAATTCCAAAAAAAGAAAATATTTTCAGTGTGAGGTAAGCTCCCCCAATACTAATGCAAAGCAAACGCCGCACGTCTCCAAAGCGCAGCAGGGGTTAATTTTTACATTCCAGTCCAGAAAAATAATTTCTAATTGGAAATATGACCTCATGGGCACTGTAGCACGCTGAACCGATGCTGAAATGTATACACTGTAGTGGGTGCTGTTAATGACGGGCAGCTGTAAACGTAGGGTGTGGTCAACTTAAAAGGAACCGAAGAAAGAGGAGAGATCAACTGGTAGGTGGCCCAGTCGGGCCAAGCATCAGATGCTCATCAGCTCATCAGCCTGCTGCTTTCATTCCTAGGGATATTTTTATACCCAACAATCTATTTTATTACCTGTTGTCTCCGATCTAGGTCTTTCCCAGACGTATGTCTTTAAAGACACTACTTTCTGCTCATATTATGGTCTTACTAGGACAGTTGGCTTATGAGACCATGCTGAAGGCTTTTCTCCATGATTGCATCACAGAAGGCTCTGTACTTATATTAATCTGCTATCTACAATGCACCAAGTCCTCTCCCTGTAGACAGTAACAGCATAACTACCACGCTCGTAACATAGTCTTAAATTTATTCTTCATTTCCCTACCTAGCATCACTTTGTCTAACAGGAAAAAACTTCTGATGTTTCTTCCTCTTGGGTTTTCTGGGACTATAGCTCCTAACTTGCCTATCACTTTCATTGAATTAAAAAGAATATAATTCTATTTCTATTGAATAACTCATTCAATTTTCCATTGAATAACTTTTGTCAAGTTTAATACTCTATTCCTAGTATAAACACCATGGGGGAGGGGGTGTATTGTCAACAAGCAATCGCTAAGCATCGGCCACTCACGCAAGAACACTCTGAGTTTTGAAGGTTTTGCCTAGAAGGAGAGCATGATGGTCCACTGAAAACCAAGCTGACTGGTACCCGGTCTTGACTCTCATCTTGTGTTCCGCTCCAG
Seq C2 exon
ACAACCGCCAGGGTCTGTGCTTCGCCGAGGTACTGCAGACAATGTGTCAGATGGCCTCCAGTAGCCGCAACCTCGTCACAAAGTCGGAGTGCTGCTGTGACGGTGGCCGAGGCTGGGGCCACCAGTGTGAGCTGTGCCCACTTCCAGGAACCGCCCAGTACAAAAAGATATGTCCTCACGGCCCAGGATACGCCACTGATGGAAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024598-Fbn2:NM_010181:56
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.3)
A:
NA
C2:
PF0068312=TB=WD(100=62.9),PF0764510=EGF_CA=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAATGCAGGACTAAGCCAGG
R:
CTCTTCCATCAGTGGCGTATCC
Band lengths:
326-1604
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: