MmuINT0062979 @ mm10
Intron Retention
Gene
ENSMUSG00000024598 | Fbn2
Description
fibrillin 2 [Source:MGI Symbol;Acc:MGI:95490]
Coordinates
chr18:58018737-58020498:-
Coord C1 exon
chr18:58020370-58020498
Coord A exon
chr18:58018857-58020369
Coord C2 exon
chr18:58018737-58018856
Length
1513 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
3' ss Seq
TACGGGGGTTGTTTTTGCAGATG
3' ss Score
8.25
Exon sequences
Seq C1 exon
ATAACAATGAATGTGGGTCTCAGCCTTCCCTCTGTGGTGCAAAGGGGATCTGTCAGAACACTCCTGGGAGCTTCAGCTGCGAATGCCAAAGAGGGTTCTCTCTGGATGCCTCTGGGCTGAACTGTGAAG
Seq A exon
GTGAGTCCACGTGCACAGGGAGCCTGGGTGTGGGGGCTTCAGAAATGGTTCCATAAAGCATGGGCCATTCAAGCCTGAGCTCAGATCCCAGTACCCAGGTAAATGCCAAGTGGTCGTGGGACCTCTTCTGTAATCCCCATGCCCTGGAGGCAGGATTGGAATCTGTGCAGCAGGCAGGATAGCTACACTAGAGGAATCCGCACGGTCTGGGTTTAGCAAAAGACCCTGTCTTAATATACAAGGTATAGCACAATACAGGAACACATACACAGGCACACACACACACACACACACACACCCCTCCCTGCGTATCCACATTTACCCATGCACAAAAGAACATGCATATGCATACACACCACATACATATACACAGACAAAAATAATATTTAGACTCTGCACCCATGGTGCCTCCCACACAATAGGTATTTTTCTCTTAGGAAATCCAAAGGAACAGCTGATGGGGAGAAAAATAAGAAAACTATCACATGGGGGTCTTCAGTGTTTACGTGGCACGTGCTGACGTCACATTCAGGAAGGCAACGTTAGCGTTGTATGTCTCGGATTCTGACACCAGCCACATCACCTTTATGCTTTTGCATTGTGTTATAGTTTATATTGTCCTGTTATCCTTTTTTAAAAGTTATTCCTAGAAATAGAATGGTTTTCCATTCTAGATACAATCAAAATGTGAAATATGCTCTTTGTACGAGTTATAGGACTTTTACATGCATTTTCAGCCCTTTTTATTTAAAACTTTTAATTTTTTTGTATCTGAAATCAATAGACATCGAAGCATTCTGAGCCTACAGCTGCTTGCCATGTGTGAATTCAGCTCGTGACCATCCACATAAAATACCATTTATTAATTATCCATGTAAATTTGTTACACACACATCAGACATGCCAATTTTATTTCACTCTTTTGGGGTAGATTTCAAAGCCTTAGTTGTCATTCCAAAAGTGTATGCATATATTAACAAAGAAATTATTCCATATGTCGTACCACATCTTGCCTAAAAATAACAACGAATTCAAATACTTTAAAGGGATTTGCATCTAATTAGTCTTGACTGACAATAAAAAAATATTTGCGTGCAAAGCCATTATATTTTACAGATAACTCCTTAGTGCTTATATCTTCTCCGCAATGGGGATTACACATGAATCACTTTTGAATCAACTACAATCGTTAATACATAATTTACCAAATAAATCATACCACATGGAGCTAGTCAATTCAAATGTACCACATTTGTGGCGACTATTGTTGATTTGCTGAAACTAAGCTGTGACTCGGAGCCCTGGTGTGCTGTGGTTGCTGGGACAGCATAAGAATAAGGTGATTTCTTATCTCAGCCATTCATTCCTTGCACCATCACTGACTCAGAACCGTGCTGAAGAAAAGCCCAGTCCCTCCATAAGCTGTGCGTTGTTTATTTGTTCCCATTAAAGGTTGTGTTTGAGATGTGTTCACCAAGGGAGTGTGCAGAGTGTACGGGGGTTGTTTTTGCAG
Seq C2 exon
ATGTCGATGAGTGTGATGGGAATCACAGGTGCCAACACGGCTGCCAGAATATCCTGGGAGGCTATCGGTGCGGCTGCCCGCAGGGCTACGTCCAGCACTACCAGTGGAACCAGTGTGTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024598:ENSMUST00000025497:61
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.5),PF0764510=EGF_CA=PU(0.1=0.0)
A:
NA
C2:
PF0764510=EGF_CA=WD(100=95.1),PF0764510=EGF_CA=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAATGAATGTGGGTCTCAGCC
R:
CAACACACTGGTTCCACTGGT
Band lengths:
246-1759
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types