DreINT0010656 @ danRer10
Intron Retention
Gene
ENSDARG00000098237 | FBN3
Description
fibrillin 3 [Source:HGNC Symbol;Acc:HGNC:18794]
Coordinates
chr22:4074519-4076410:-
Coord C1 exon
chr22:4076282-4076410
Coord A exon
chr22:4074639-4076281
Coord C2 exon
chr22:4074519-4074638
Length
1643 bp
Sequences
Splice sites
5' ss Seq
ATGGTTGGT
5' ss Score
5.29
3' ss Seq
ACAAATCTGTTTTCTTACAGACG
3' ss Score
8.82
Exon sequences
Seq C1 exon
ACAACAACGAATGCAGCAATCAGCCGAACATATGCGGGTCCCGTGCCTCCTGCCTCAACAGTCCCGGCAGCTTCAACTGCGAGTGCCAGAAGGGCTTCTCTCTGGATGCCACGGGACTCAACTGTGATG
Seq A exon
GTTGGTGTCCCATTTTGTTTTTTGGAGAGGATTAGCATCATTGTTGATCAATAGCTCTATTTGGACTTGCAATGGGCTATATGCACAGCAAGTGTCGCCTCACAGCAAGGTCACTGGTTCAAGCCCCGGCAGGGCCAGTTGTCATTTCTGTGTGGAGTTTGCATGTTCTTCCCGTCTTGGTGTGGGTTTCCTCATAGCGGTTCCAGCCCTAACACATGCGGTATAGGTGAATTGGGTAAGCTAAATTGGCCCTAGTGTATTTGTGTCAATGCAAGAGTGTATGGGTGTTTCCCAATGCTAGGTTGCAGCTGGAAGGGCATCCGCTGTGTAAAACATATGCTGGATAAGTTGGCAGTTATTTCCACTGCGGCGACCACTGATTATTAAAAGGGACGAAGTCGAAGAGAAAATAAATGAATGACTAATTAACTGATGTTAGATGCACTTCTGCCAAAAGTGAAGTTTCACAAACTAATTTCGAGACGAGCTTGTGTTATAATCAACTACATCCTAATCGCTAATCATTAGCTAGCATATCAGATCATTAGCGGGAGGGCCAAAGGTTCAAGTTGTAATTGAGCCAGTCTGTACTCTCTGCACGGAGTTTGCATGTTCTCCCCGTGTTTGCATGGGTTTTCCCCGAGTACTCCGGTTTCCCTCAGTCTAAAAATGTACATACGCAAATTTTTATAACATTCACAAGCACTTAACACATACATACTGAATCAATTAGAACCACCATATTAATCAAAGTATAAAAAAAACGAAGTAGGGGACTCTCAAGAAATACCTGATGTCGTACCCCTCCTAATGCTCATTAAGCAGGAGGGAACCTTGGGCTTATTATCTCCAAGCTCAGGGTTTTCTCCTGGGACAGCATGCCAAACGTGCTATCATAGTCGAGCATTATCTAAGTGTAAACTCTTGAAATAAATGAACGAATGTCCGTCTAACCCCAGGTAGCCTAAAGTCATTTGTTTTTAACGGGAGCTTATGGCAAGGTCTGGCGAAAGCACCGGGGCTCGTTTTGGATGGTGTGGTCTTGAAGAAGTGTTGAAATGAGGTCAACTTTATGGTTTTAAGATATGACGCAGTTCAGCAGCAAGTCATCAAAACGAAAGCAGAGGTTGATTATTGCTTTGGGCGTCACAGTTAATAATGTAGGATGTGCCCAAGTTAGCGTTACCGTGAAGACCAAGGCTATCAAACATCTTCTATAGACAGCATGTTGAAATCAGACTAGCACTTAAACATGAGCTTGTAAGCTTCACTACACGAACAGCTTTTGATTGGTTTGTTATAGAAGACAATATTAAAAGACGATGCTGAAAAAGCAGTGCTGTTGGTAGGGTGGCCAGAGCAAATTCTGAAGGCGACCATGTGAATGCACAGTAAAATTGAAGGGTCAATCATTGTGCTCATAATGAATGACTGGAATCTTTTTGGATGGGAGATTAAAATACACAGGCATCTTAGAGGAGATCAAGTGTAAACAGGAGGACCAAAAAATGGATATGGGCCAAAGGATCAGATCTGTGCATTAAGACTTCTAGTGTAGACACAGCCTATGCGCGATCCCAGAATCCCAATAGAAACATTTATACTTCTATTAGATCAGTTTCTACAAATCTGTTTTCTTACAG
Seq C2 exon
ACGTCGATGAATGCGGTGGAAACCACCGGTGCCAACATGGCTGCCAAAACATGATGGGAGGATATCGCTGCGGCTGCCCACAGGGTTACGTTCAACACTACCAATGGAACCAGTGTGTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000098237:ENSDART00000167748:40
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.5),PF0764510=EGF_CA=PU(0.1=0.0)
A:
NA
C2:
PF0764510=EGF_CA=WD(100=95.1),PF0764510=EGF_CA=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAACGAATGCAGCAATCAGC
R:
CCACACACTGGTTCCATTGGT
Band lengths:
246-1889
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]