Special

MmuINT0083775 @ mm9

Intron Retention

Gene
Description
integrin alpha 6 [Source:MGI Symbol;Acc:MGI:96605]
Coordinates
chr2:71678843-71679207:+
Coord C1 exon
chr2:71678843-71679032
Coord A exon
chr2:71679033-71679123
Coord C2 exon
chr2:71679124-71679207
Length
91 bp
Sequences
Splice sites
5' ss Seq
CCTGTAAGT
5' ss Score
7.52
3' ss Seq
CAAGGCCTTTTCTGCCGTAGGAG
3' ss Score
7.43
Exon sequences
Seq C1 exon
TCAAAAAGGCATCCCAGAATTAGTCCTAAAAGATCAGAAAGATATAGCTCTGGAAATAACGGTGACCAACAGCCCTTCGGATCCAAGGAATCCCCGGAAAGATGGCGACGATGCCCATGAAGCCAAACTCATCGCCACGTTTCCAGACACTCTGACATATTCCGCTTACAGAGAACTGAGGGCTTTCCCT
Seq A exon
GTAAGTGTTTTTGAGAAAGCAGCAGGGAGGGAAAGACCGGTGTCACATAGCACGTGAACAAACCGTGACCCCAAGGCCTTTTCTGCCGTAG
Seq C2 exon
GAGAAGCAGCTGAGCTGTGTGGCCAACCAGAATGGCTCCCAAGCCGACTGTGAGCTCGGAAATCCTTTCAAGAGAAATTCCAGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027111-Itga6:NM_008397:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact

ORF disruption upon sequence inclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.344 A=NA C2=0.142
Domain overlap (PFAM):

C1:
PF084417=Integrin_alpha2=FE(13.2=100)
A:
NA
C2:
PF084417=Integrin_alpha2=FE(5.7=100)


Main Inclusion Isoform:
NA


Main Skipping Isoform:


Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
ALTERNATIVE
Zebrafish
(danRer10)
LOW PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAAGGAATCCCCGGAAAGA
R:
GATTTCCGAGCTCACAGTCGG
Band lengths:
173-264
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types