MmuINT0098031 @ mm10
Intron Retention
Gene
ENSMUSG00000020691 | Mettl2
Description
methyltransferase like 2 [Source:MGI Symbol;Acc:MGI:1289171]
Coordinates
chr11:105128741-105130496:+
Coord C1 exon
chr11:105128741-105129075
Coord A exon
chr11:105129076-105130446
Coord C2 exon
chr11:105130447-105130496
Length
1371 bp
Sequences
Splice sites
5' ss Seq
GAGGTAACT
5' ss Score
8.77
3' ss Seq
ATGGTTCCTTTCTGTTGCAGGTT
3' ss Score
11.66
Exon sequences
Seq C1 exon
TTGATTATGAAGTCAATGCCCATAAATACTGGGATGACTTCTACAGAATCCATGAAAATGGGTTTTTCAAGGATAGACACTGGCTTTTTACTGAGTTCCCTGAATTGGCACCTAGCCACAGTCACCTGACGGGTGTACCCTTGGAGAAGCAGAGGAGTGACGTCTGTGAGGACGGACCTGGCTTGACAGCAGAACAGCACAAGTGTTCTTGTGCCAGCCCTGGATGTGAGACTCAGGTGCCTCCCTTGGAAGAGCCAGTGACTCAGAAGCTCGGTCACCTAGAAATTAGTGGTGAGGAATTTCCTGGCTCCTCTGCCACCTACCGAATACTTGAG
Seq A exon
GTAACTTGATTTTTCGAATAATAGAGTTAGTGAAGATGCCACATTTTACTCGCAGATAGACTAGAAAGGGTGACCCAGAGTGTCTTCTGTCAGATCAACTTGGCTAGATTTGAGCATCATATCAGCGTGGAATGGTCACCCTTGTTTGTTTGTTTGTTTGTTTGTTTGTTTAAACCGAGAAAATACCTAGGTGCTTACTATCAGGGAAATTCATATACAAGGGCCTACCAACTCCACTGGAAGCTAATTCTAGAGCTGGTAAAACTTGAATTAAATCCATTGCCATGAGGGGGGGCAGTGCTGGGAGTTGAACCCAAGGCCTCAAACAGATTAGCTCTTTACCACTGAACTAATCTCGTAAGCTCATGTCACTCCTAGAGTAAAGGAGTACTTGGTCTAACTGTAAGGAACGTTGCAAAATAGCTAAGAAGTATGTCTGCCAAGTAGCCCTCCATAAAGTTTACAGTTTGTGTTGCTGCAGAAAGCTCTACATTTAGCACAGTGCTACAGTGTAAATGTTCTCAGCTGAGGCTGTTGTGGGAAGCAGAGGTCCTTGTCCTCACAGATACACATAGGGGAACCTGGAAGGTTAGCACTCAGAGTTGTTCCTTCAAGGGAAGGAATGCAGGACTTATTACTTGCCTAGAAGGCTGGGAGCAGAAGTGGTTAATGGTGTGGTGACCAAACCAGACGCCTCACCCTTATCATAAGTTCTTTTTCTCAGTCGACTTATAGAAGATGTCACATGTACTGTACAAAGAGTTTCAGTGTATTCACATTGATGTTTATTCTGTTTCTTTATGGAGATTTATGGATGCTTTAGTGTACACATGGGCAGGAATTAATCATCACCACTCAGGGTCGGCCTCCCTGGGTGGTGTTGAGCCAACACTAGCTGTGGAGTCACGGTGAACCTGCCTTCTTGCCTCCCAGGTCATCTATGCTGGCCATAAAGGTCGCAGAGACCCTGCAGTCTATCTTTCTAATAATGGTGTAGTGAAATCATTAGGAAACTAATGTGTCTGCAAGGTTTTTGCTGGAACTCAGGATGTAAAAGTAGCTTGTGTTCCTTTTTTTAGACTAGCTTTCTTCAGCCAGTGGAAGCTGGTGTTCTTGTCCTTTACTAAGTCTCTTTAATTAGAGTCCATGAGAGATCAGGAAATGCCATAGGTCCTATACATTTCCTAGAACAATTCTTAAAAGCTGGGCATGACAGTGCCTGTAGTCTCAATACTCAGGAAGCTAAGGCTCGAAAACCATAAGTTATAGACCATCCTGGAGCCTGTTAAAAAAAGAGAGAGAGAGCAAGAAGAAAGAATGGCGGGGAAAGGGTTAATAACTTCTGGGACTAATGGTTCCTTTCTGTTGCAG
Seq C2 exon
GTTGGTTGTGGTGTAGGAAACACAGTCTTTCCAATTTTACAAACTAACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020691:ENSMUST00000021030:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.134 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF134891=Methyltransf_23=PU(15.0=25.0)
A:
NA
C2:
PF082427=Methyltransf_12=FE(15.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTCAATGCCCATAAATACTGGGA
R:
TGTTTCCTACACCACAACCAAC
Band lengths:
347-1718
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types