RnoINT0091767 @ rn6
Intron Retention
Gene
ENSRNOG00000006131 | Mettl2b
Description
methyltransferase like 2B [Source:RGD Symbol;Acc:1310240]
Coordinates
chr10:93356237-93358023:+
Coord C1 exon
chr10:93356237-93356586
Coord A exon
chr10:93356587-93357973
Coord C2 exon
chr10:93357974-93358023
Length
1387 bp
Sequences
Splice sites
5' ss Seq
GAGGTAACT
5' ss Score
8.77
3' ss Seq
CTGATTCCTTTCTGTTGCAGGTT
3' ss Score
11.99
Exon sequences
Seq C1 exon
CTGATTATGAAGTCAATGCCCATAAATACTGGGATGACTTCTACAAAGTTCACGAAAATGGGTTTTTCAAGGACAGACACTGGCTTTTTACTGAGTTCCCTGAACTGGCACCTAGCCACGATCACCTAGTGAATTTGCACTTGGAGAAACAGAAGAATGAAGTCTCCAAACCTAGAAGCAGTGAGGATGGACCTGGCTTGGCAGCAGAACAACACAAGCGTCCTTGTACCAGCCATGGATGTGAAACTCGGGTGCCTCCCGTGGAAGAGCCGGTGACTCAGAAGCTCACCCACCTGGAAATTTGTGCTGACGACTTTCCTGGCTCCTCTGCTACCTACCGAATACTTGAG
Seq A exon
GTAACTTTATTTTCCTAATGGAGTTAGTGAAGATGTCACATTTTACACTCAGACTAGCAAGGCTGACCCAGAGTGTCTTCTGTCTGATCAATTTGACTAGATTTTAGCATCCTACCATTGAGGAATCGTCACCATTCTTCTTTTGAATTGGGACAATACCTAGGCAGGTCCTATTAGGGAAATTCGTTTATAAGGGACTACTAACTTCACTGGAAGCTAATTCTAAAGCTAGTAAAACTTGGAATTAAGTCCAGTGCCATGAGTGGGGGCAATGCTGGAAATTGAACCCAAGGCCTCACACGGGTTAGAGGAGCGCTTTACCACCTAGCTAATCCCTGTTACCTCCTGTGAGATGCTGCATGAGCTCATGTCCCTCCTAGAGCACAGGGAGTACTTGGTCTAACTGTAAGGAACTTTAGGTAATGTATATAAAATGGCTAAGAAGTATGTCTGCCAATGGCACTCCGTAAACGTTTACAGTTTTTGTGCTGCAGAAAGCACTATATTTAGCAGTGTTACTATGTGAACGTTTCAACTGATCCTGTTGTAGGAGACAAGGAGATCCTTGTTCTCACAGATAAGTCCTAGGGGAACCTGGAAGGTTAGCACTCAGAGTTGTTCCCCTGAAGGAATGCAGGACTTAATGCTTGCCCAGAAGGCTGGGAGCAGAAGTGGCTAATGTCTGGTGACCAAACCAGACCCCCTGACCCTGATCATAAGCTTCTTTTTCTCAGTCAGTCTATAGAACCTTTATAGAAGGTGTCACGTGTACTGTACGAAGAGTTTCAATGTATTTACATTTGTTCTCTATTCCTCAAAGAGATTTATGGATGCTTTCTTGTACACATGGGATTGAATTAGTCATTACCACTCAGGGTCAGACTCCTGAAATTTGAACCAACACCAACACCAGCTGTTTAGTCTTGTTGAACCTGCCTTCTTGCCTCCCAGATCGTCTATGCTGGCCATAAAGGTCTCAGAGACTTTGCAGTATATCTTTCTAATCATGGTGTAGTGAATGAAGCTCATCAGGAGAATAATTTATCTACAGGGCTTTTTGCTAGAACTCAGAAAGTAAAAGCAGCTTTGTGCCCTTTTTTTAGACTAGCTTTCTTCAGCCAGCGAAAGCCAGTGTTCTTGTCTTTAACTAAGTCTCTGATTAGAGTCCATGAGAGATGAGGAAAGGCCATGGGTCCTATTTAGGTCAGGTCGTTATACCTCCCCAAGTACAGCTCCCAAAAGCTGGGCATGACAGTGCCTGTAGTCTCGGCACTCAGGGAGCTGAGGCTTGAAAACCATTAAGTTATAGACCATCCTGGCCCCTGTTGTGGAAAAAACAAGAAGAAAGGGGAAAGAGTTAATGACTCCTGATTCCTTTCTGTTGCAG
Seq C2 exon
GTTGGCTGTGGTGTAGGAAACACAGTCTTTCCGATTTTACAAACTAACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000006131:ENSRNOT00000008140:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.282 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF134891=Methyltransf_23=PU(15.4=24.8)
A:
NA
C2:
PF134891=Methyltransf_23=FE(8.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCCATAAATACTGGGATGACT
R:
TGTTTCCTACACCACAGCCAAC
Band lengths:
356-1743
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]