Special

MmuINT0101995 @ mm9

Intron Retention

Gene
ENSMUSG00000021987 | Mtmr6
Description
myotubularin related protein 6 [Source:MGI Symbol;Acc:MGI:2145637]
Coordinates
chr14:60903754-60908514:+
Coord C1 exon
chr14:60903754-60903882
Coord A exon
chr14:60903883-60908379
Coord C2 exon
chr14:60908380-60908514
Length
4497 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGGA
5' ss Score
8.24
3' ss Seq
TTTTGTCTTTTTGAAATTAGGCT
3' ss Score
6.85
Exon sequences
Seq C1 exon
GTCTGTGAGACTTATCCCAGAGAGCTGTATGTTCCTCGGACAGCTAGCCGGCCGGTGATCGTGGGCAGTTCCAACTTCCGGAGCAAGGGCAGACTTCCGGTCCTATCCTACTGCCGGCAGGGCACTGAG
Seq A exon
GTAGGAACCTCCTCTGCTTTATAAACGTGGTGAACTGAAGTTCTGCTCTAAGCTTCTGGGTGAACACTGTTTTGTTTTTGAGATACGATCTCACTATGAAGCTCTAGATGCCCCATAGCATACTATGTAGACCAGACTGGCCTTGAGTTTATGGGATCTGCCTGTCTCTGCCTCCTCAACCCTGGGGTTAAAGGCACATGCCACCACAGCTGCCAGTAAATATAAATATTAACTTTCACTTCGCAGGTTTGCTGTTGTAATGTTGGTAACAGAGACATGCTGGCTTTTCACTATCGTTTCTGAAGTTTTTAAAACAAAATTACCCTGAAGTGCTCCCAGAAATTCCTTAATAATGGGACCAGTGAATAGATAGGTTCTGTTTCTTTTCTTCAGGCTTCCTTTAGTCCTGCGTGTACGTAGAGAAATCGGATAGCTTGCTTGTGCCTAGGCAAGCACTGAAAGCAGGAAGAGAACCCAGGGCTCTGTCAGCAGGCCTCACATGGAAAGGACTTTGCAATGAGGAGGTGGAGGAGGCATGCCAACTTTGTAAACTGATTTTTAAATACATTCCCAATTCCCCACCCCACCCAGAAGATTTTTCTTTTTCCTTGGATTTTGGAATTTCACGGTTCTCTGCCTCGGTATGTCATTTACAGACAGCCCAGAAACTCAGGTTCTGCAGCCATTCTTTTCTCTGTTGGTTTTCTTTGTAGTTTTTCTTTTTTTAGCTTGTATAAATTGACAGACTTCCTATGTAGCTCCAAGTCTGTTTTCTGGAAGAGTTCCTTAATTCTATTTCTCTCTCAACTCTCTGATTCTTTATTTCTGAGACTGTGTGACGTTTAAGGGTTCTTTCTCTACTAAATTTCTTTAGTCAATTTTCTGCTGTTCTCTGATTTGGAGTCACCAACTCTCACGCAGATTTTTTTTTTGAAGGTTCATGACTTTCTGTTAAATGACATTTTTTTCAATTTTTTATTAGATATTTTCTTCATTTACATTTCAAATGCTATCCTGAAAGTCCAGACTTTTTTTTTTTGGTAGGAATTCTGTGTGGCTGTCTCTCCCTCTCCTCGTGTTTTGCTGTTTGGAAGTTTGCATGACTGACGTTGTATGCCTTTGCAGTTTTAAATGTTTCTGCTGTGCACTCGGCTTCCTCACCGAGGCTGTGCTTTTGCTAGTGTGTCAGCAGAAGGACTTGGTGGGATGTAACAGTCAGAACTCACACTCTGCTGGGTGGGCCATATCTAGTCCTCTTTGTAGACTAAGTGCTCAGTGAGAAGGAACCTGGAGGTCACAGCTCATCTTTATGAGATCAGCCACACCCGGCTTCCACGCAGGTGCCAGCTCATGCGCTCTGACCTTTCAGCTAGATTCTCCCAGCTCCTTTCTGTAGCAGGCACTTCCTCTGTCAAAGCAGTTCTCAGGCTGCTGTTGCCCCCAAATGTCACAGCACTGTTGTTGGAGTTTCTTTGTTGATGCTTCCCTGGTGGTCCTATATGTCTTATGTTTGTTAGAACCTAGGTCAGGTAAGTTTTAAACAGAAGTCTAATGCTAGTACCTTAAGTCCTAGGGTGTTACCTGGTCACCTTTGACACACCTTGTTAGATTACACTGTTTATTGGAAAGGTAGGCCGGAAAATACTTGTGGTTAACTTAGTAAACAAAAGATAGGTGTACCAGGAGTGTAGAGCATAGGATTCCTTTACAACAGCAACCCAAACCCTGCTTATGCTCAAAGAACTAAGAGGCCACATCCAACAATAAAAAACTGACTAAAAACATTTACAGAAAACAGGAGAGAACGCTTGAACTCTAAAAGCAGCACAATGGTCATCATTTTCTTCTGCCATTGTAATTTTTGAGATTGTATTTTGTGTGTGCATATAAAATGTTCAAACGTTTATACTTGTAACACTTTGTCCCGATGATACGCTATTAGAATATTTCTGTAGAGTTAAGTTGGAGGTAACATGGGTAAGATTACAGATGGGTATATACTTCTAAATCTTCTACTTTTTTTTTTTTCTGTCAAGGTAGGGCAGGGCAGGGTTCCAAGACAGGGTTTCTCTGTGTAGCCCTGGCTGTCCTAGAACCCACTCTGTAAACCAATATGGCCTCAAACTCACATAAATCCATCTACCTCTGTCCCCGAGTATGCCTCCCCTTAAATTATCTTTTCAAATCTTTATGTCTCACTTTATAAAAAGCTTTGTGGCTTTTAGTAGGGAAATAAAATTTGAGCTGTAAGTTTACTTTTTAATTTTTATTTTACACTTTGTCTTAGTTTGAACTTTGTAGACCTGACCCAGGAGGCTTTAGTGAAGAATTTCAGTATGTAGCCTAGGTGTTTTGGTGAAGAGACACCATGACCAAGGCAACTCTATAAAGGACAACATTTAATTGGGACTGGCTTATAGGTTCAGAGATTCCATCCATTATCATATAGGCAGGAGCATGGCAGCTTCCAGCCAGGGATGGCAAGGGAAGAGCTGAGAGTTCTACATCTTGATCTGACTGCAGCCAGGAGAAAGCTGACTCTTCCACACTGAGGAGAGCTTCAAAGCCCACCTGTCACCCCACAGTGACTCACTTCCTCCAACAAGGCCACATCTCCTAACAGTACCATTCCCTATGGGCCAAGCATATTCAAACCAGCACGCACATATACATGCTTTGCTTGAATGTTTGTGTACCATGCATGTGCCTGGTGCTTATAGGATCCCCTGAAACTAGAGTTACAAAAGATTATGAGCCTCCATGCAGGTGCTGCCCTCTGGAAGAGCAGTGGGTGCTCTTACCTGTCAGACCATCTCTTCTGGTCAAGATGAAAAGTTCCTGGTAAGGGAAAGAGAAATGGTGCAGGGGTTAAGAGTGCTTCCTGCTCTTCCAAAGGACTTGAGTTCAGTTCCCAGCAACCATGTCCAGTAGATCACAATTGCCTGTAATTCCAGCTCCAAGGCATTAAATACTCCCTTCTGGCCTCTGAGGGGACTCACATGCAAGTGGCATGCACTTGCATAGGTATGCACTCATAAATAAAAATCTTAAAATTTCTTATTCTATATGTACTGTTAGCCCATTTTCTTTACTTGAACTTGAGCTGAAAGAACCTTGTAGCTCATTAAAAACCTGGAATGCAGATGTTTCCTTAGTGTCTGCTCCGTGATAGACAGCTAACCAAGTGCTACTCCTTAGGGCCACAATGTTCTTAATTTATTTTTGATTGTGTGTGTATGTACAAACTAGGTAAAGAAACATTTATTTTTCTTAGAATAAAATATTGGGAAGTGTCTTAAGGTTTTATTGCTATGAATAGATACTGTGACCACAGGAACTCTTTTTTTTTTTCCATTTTTTATTAGGTATTTAGCTCATTTACATTTCCAATGCTATACCAAAAGTCCCCCATACCCACCCACCCCTACTCCCCTACCCACCCACTCCCCCTTTTTGGCCCTGGCGTTCCCCTGTACTGGGGCATATAAAGTTTGCAAGTCCAATGGGCCTCTCTTTCCAGTGATGGCCGACTAGGCCATCTTTTGATACATATGCAGCTAGAGTCAAGAGCTCCGGGGTACTGGTTAGTTCATAATGTTGTTCCACCTATAGGGTTGCAGATCCCTTTAGCTCCTTGGCTACTTTCTCTAGCTCCTCCATTGGGAGCCCTGTGATCCATCCATTAGCTGACTGTGAGCATCCACTTCTGTGTTTGCTAGGCCCCGGCTTAGTCTCACAAGAGACAGCTACATCTGTGTCCTTTCAATAAAATCTTGCTAGTGTATGCAATGGTGTCAGCGTTTGGATGCTGATTATGGGGTGGATCCCTAGATATGGCAGTCTCTACATGGTCCATCCTTTCATCTCAGCTCCAAACTTTGTCTCTGTAACTCCTTCCATGGGTGTTTTGTTCCCAATTCTAAGGAGGGGCATAGTGTCCACACTTCAGTCTTCATTCTTCTTGAGTTTCATGTGTTTAGCAACTTGTATCTTATATCTTGGGTATCCTAGGTTTGGGGCTAATATCCACTTATCAGTGAGTACATATTGGACCACAGGAACTCTTATGAAGGAAAATATTTTACTATGGCTGGCTTACATGTTCAAAGGTTTAGTTCGTTATTGTCATGGCAGGAAGCATGGCTGTATGCAGGCAGATATGATGCAGGAGAAATAGCTGAGAATTCTATATCTGGATCAGCAGCAGAAAGACGGTCTGGCTTGAGCTTCTGAAGTACCTCATGTGATACAATTCCTACGACAAGGCCACAGCTACTCCAACAAGGAAGGCCACACCTTCAATACTGCCACTCTGATCTGTGTAACCCCCACAGGAAGTATAGGCAGCATCTAGATTTTGAGAAGTATTTAAATCAAATAATTTTTAAAAAGTTAATACTATCTAAATTTATTTCTGACTTTTAAATAGATTGTGTGTTTGATTGTAATACTTTTGAGTCTTTTTATAAAATCTGTTTTTTGTCTTTTTGAAATTAG
Seq C2 exon
GCTGCCATTTGTCGATGTAGTCAGCCATTGTCAGGCTTCAGTGCCAGGTGCCTAGAGGATGAGCATTTGCTTCAAGCCATTAGTAAAGCCAACCCAGGAAACCGCTACATGTATGTTGTGGATACCAGGCCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000021987-Mtmr6:NM_144843:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF066029=Myotub-related=FE(12.2=100)

							
A:
NA

							
C2:
PF066029=Myotub-related=FE(12.8=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000022563f1139A





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000022563
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr13:25261803-25265818 
LOW PSI
HsaINT0106298
(MTMR6)
Human
(hg19)
chr13:25835941-25839956 
LOW PSI
HsaINT0106298
(MTMR6)
Rat
(rn6)
chr15:40580397-40584526 
ALTERNATIVE
RnoINT0095401
(Mtmr6)
Cow
(bosTau6)
chr12:34185146-34186585 
LOW PSI
BtaINT0096137
(MTMR6)
Chicken
(galGal4)
chr1:176347524-176348531 
ALTERNATIVE
GgaINT0115693
(MTMR6)
Chicken
(galGal3)
chr1:181395216-181396223 
LOW PSI
GgaINT0115693
(MTMR6)
Zebrafish
(danRer10)
chr24:24902420-24903993 
LOW PSI
DreINT0098735
(mtmr6)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"