Special

MmuINT0103233 @ mm9

Intron Retention

Gene
ENSMUSG00000020900 | Myh10
Description
myosin, heavy polypeptide 10, non-muscle [Source:MGI Symbol;Acc:MGI:1930780]
Coordinates
chr11:68611752-68614421:+
Coord C1 exon
chr11:68611752-68611958
Coord A exon
chr11:68611959-68614316
Coord C2 exon
chr11:68614317-68614421
Length
2358 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGG
5' ss Score
9.99
3' ss Seq
TCATCCTTACCTCTCTGCAGAAT
3' ss Score
9.43
Exon sequences
Seq C1 exon
TTCAAAGCCAACCTGGAGAAGAACAAACAGGGCCTGGAGACAGACAACAAGGAGCTGGCGTGTGAGGTGAAGGTGCTGCAGCAGGTGAAGGCGGAGTCAGAGCACAAGAGGAAGAAGCTGGATGCCCAGGTCCAGGAGCTCCATGCCAAGGTGTCAGAGGGTGACAGGCTCAGGGTAGAGCTGGCCGAGAAAGCAAACAAGCTACAG
Seq A exon
GTATGGGCTCTGGCGGCGTGTTCTGTTGCATACCTGGAAAGTGTTGTCCCGATTAAATATGGCAGCTCGAGGGTATGTGTGTGTATGTGTGTGTGTGTGTGTGTTTAAGATAAACTTAAGGTAAACAGTCCCTTTAAAGAATAAGACCGGTGAGTTTAGACCTGGCCAGTACGGCTGTGGCCGAGGGCATCTCACCTTCTCCTTAGTCCAGGAAACACAAGAGCACTCAAGAGACTGGCTGTGCACAGACGTGTTTAAAGTATTTCATTGGCACAGGTTCTTTTTCCTGATTTGGTTGTCATGTATTGTAAACCATTAAATACCCTGGGACCAAAATCGGTGTCTTTCTCATTTTTCCTCAAGAAATGGAGCCGCACATGGGCTCAGCTTTAAAGCTGCTCACTGTCGGATGTGGGCAACAGCACCGATCAGAGACTCCATCAGTGTCTGGTAATGGGCTCGGGTGTAGCGAGTAAAGTGACTTCCCAGAGGAGTGTCTGTGCTGCTGCCCACTGCACAAAGGACAGAAGCTGCCTGTCGCTTCGGTTTGAGGTCTCCCTGGGCTTCAGTGGTTTGCTCTAGTGAAGGAACACAGGACAGGGAAGGAAGCTGGAGCTAGTAGACTCTGTGGTGGCCAGCTGGGGAATCTCCAGCCCAGTCCCACAGCAGGTACCCAGTTTCTCCAGCAGGATGGGGACAGTGTGTCAAGTGTCGCCCTTCAGGGATCCTGTCAGACACTCAGCAAAGTAGGCTGTTGCTGAGAGGTGGGTCCTGTAGGCCCTCTGCCTGGAAGGACAGCAGGCACTCAGCACAGGCCACCTGATTTGCCCAGATAATCTAGGCACAGTGGACCTAGAGAATTGTAAGACCCCACGTGAAATCCAACTTTCTGAATCTAGCCAGGGATGTTAGAAGCAGGCCTTTTAAGGAGAACAGCCTCTGGCCTGCTGTGTACAGATATCCCTGTATGCCTGTGTATGGGGCTCTCATGGATCTTGGAAGGTGTTCCTGAAAGGCACTGTTAGAAACAGTGTTATGACTAAGGTGGGCGACATCAGTGGTTTCCCAGAAAGCACTGGGCTCCTACGGACATAGCCACTTCCCTCCATTGCATCCTCACACAGCTCCACAGGCTGGGCTAGGAGGCTGCAGGTCATAGGAGCTAAAGGCCTCCTCTCTGGCTCTCTTCAGATCTAAGGTAGAACAGGCGGTCCCTCTTAACACCAGAGATCTTCCCCAGTACCCTCCACCAAGAGCAGGGAAAAATGAGCTCTCTGAAGGATGTTGCTACAAAGTAATAGAAGCAGGGCTGTCTTGTTAGGCATACAGTGTGTCTTCCATGTAGCTCCCTGTAATAATACAGCCAGAAGACAAGTGAGGACAGGCTACCCTGCTGCTCTTCCACTTCATATGCACAGCACTCACAAAAGATTTTAAAATAAAGACTTTTCCAACCCTTTTAGAAAATTGTTTTGAATGTGCACGTGTGAGTGAGTGTGTGCATGTTTTGAGACAGTTTGTCTGTGTAGCCATGGCTGTCCTGGAACTTGCTCTTAGACCAGGAGGACCTCTCACAGAGATCTGCCTGCACCTGCCTCTGCCTCCCTAGTACTAGGACTAAAGGTGCTCCACCACTGTATATTCTTTTGAGTCTTGTCCACATGTATATCTGTGCATCACCCATATGCCCAATGCTCACCAAGGTCAGAGGGTGCAGGTCCCCTAGGACTGTAGTTACAGACCATTATGAGCTACCATGTGGGAGCTGGGAACTCTTCCAGAAGTGCAACCAGTGCTCTTACAGTCTGAGCCATCTCTCCAGCCCTTTTTGGAGACATCTTTCATTGAGGAGGAAATGGGGGAAGTATCACACTATTGCTAAAATCTGATCATCACACTGAATGTAGACCTGTTCCTAAGAGCTGGAAACATATTGGCTAATTGTTAGCATGCATATTTCCTTCTGAGTCCCTTAAATGTTGAGTTCTGTAAGAATGTAAATTCCATGTGCCCCCAGTGTGCCTAGTGTAAATTAACATGAAAGAAAGCACCTGCTGGCCCAAACTGGCCCTTCATGTCCTCCAGCTGAAGTGGTTTTATTTTGTCTTTTCGTGGCCAAAGTAAAATACAAAGAGGATCCCAGGGTCCAAGCACCCCCTGCCCTTTCAACCAGAGGCCATGGGGAGGTGGCTGCGGAGGAGGTCTTAGCTCCACCCTGGGTGGTAAGCATTATTCACTGAATTTGCTAGTTAGAATTCTCACACACGTGACACTCACGCACTGTTCTGTTCTCTATGAGCTGTGGTGATAGGTCTTTTTCTCGCTATGGAACTGAATTTCATCCTTACCTCTCTGCAG
Seq C2 exon
AATGAGCTGGATAATGTGTCAACCCTGCTGGAAGAAGCTGAGAAGAAAGGTATTAAGTTTGCGAAGGATGCAGCTGGTCTCGAGTCTCAACTACAGGACACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020900-Myh10:NM_175260:28
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.536 A=NA C2=0.343
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0157614=Myosin_tail_1=FE(13.0=100)

							
A:
NA

							
C2:
PF0157614=Myosin_tail_1=FE(4.0=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000090661





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000018887, ENSMUSP00000090661f862A, ENSMUSP00000099671
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr17:8495242-8499269 
ALTERNATIVE
HsaINT0107478
(MYH10)
Human
(hg19)
chr17:8398560-8402587 
ALTERNATIVE
HsaINT0107478
(MYH10)
Rat
(rn6)
chr10:55389713-55392029 
ALTERNATIVE
RnoINT0096322
(Myh10)
Cow
(bosTau6)
chr19:28697065-28697472 
LOW PSI
BtaINT0097098
(MYH10)
Chicken
(galGal4)
chr18:1712667-1713703 
LOW PSI
GgaINT0127259
(MYH10)
Chicken
(galGal3)
chr18:1699694-1700730 
LOW PSI
GgaINT0127259
(Q789A6_CHICK)
Zebrafish
(danRer10)
chr6:7480048-7481054 
LOW PSI
DreINT0099740
(myh10)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"