MmuINT0103258 @ mm10
Intron Retention
Gene
ENSMUSG00000018830 | Myh11
Description
myosin, heavy polypeptide 11, smooth muscle [Source:MGI Symbol;Acc:MGI:102643]
Coordinates
chr16:14230693-14232698:-
Coord C1 exon
chr16:14232525-14232698
Coord A exon
chr16:14230867-14232524
Coord C2 exon
chr16:14230693-14230866
Length
1658 bp
Sequences
Splice sites
5' ss Seq
CCGGTGAGG
5' ss Score
9.35
3' ss Seq
CTGCCTTCTTATGTCCCCAGAAC
3' ss Score
10.75
Exon sequences
Seq C1 exon
GTAAACTCCTTCGAGCAGCTGTGCATCAACTACACCAACGAGAAGCTGCAGCAGCTGTTCAACCACACGATGTTCATCCTGGAGCAGGAAGAGTACCAGCGAGAGGGCATCGAGTGGAACTTCATCGACTTCGGCCTGGACCTGCAGCCTTGTATTGAGCTGATTGAGCGGCCG
Seq A exon
GTGAGGGGCTGGCACCGTGCATGCATGGCCCATTTGTACACACCTAGTCTGAGAATGCATTCCTTGTGGACAGTGTCTCTGGCCGAGTCCTGGAGCTGTAAATGGATTCCTTGGGAACTAACTCACCTGGAACTCAGTATGTAGACAGAGGCTAGACTCTGACCCTAAGAGTTCTCCTGCCTCAGTCCCACACGTCAGGCTGGCTTCAAACTCACTGTGTAGCTGAGGGTGACCTTGAACTTCTTTCTTCCTGCCTCCAGCTCCCAAGTGCTGGGATTGCAGGCGTGTACCACCTCACCTGGCTGACACATGATTCTGACAATCCTCCTGCCTCAACCTTCCTGTGCTATGATTAGGATGTACACCACCATGATGCAATTCCCCTAGTCTTTCTCTTCTTCTTCTCCATTCATTCATTCATTCATTCATTCATTCCCAGAGTCTGTGCTTGGTCCACTGATACGTCCCAGACTTTTAGAGCCATAGTAGGCTACTAGTCACCATGTGCTAGGCCTCTTATTTTAGGGTTGAGGCTGTAACTATGAACAAGACGAGCATGGACCCTCACCCCCTAGAAGAGCCAGTGGTGAAACCAACTGACACTCGTGGCAAGGCACTATGGAAGGCAATCAGGACATGGTTTCATGTGGTGGAGACCTCAAAGTGAAGATAGTTCCCCCAGGGTGAAGGATACAAACTGACACCTTAATTTAGATCCTCTCAAACATAGAAAAACATTGCTGAAAGGGATCCTGGGTAAATTTATAAGGAAGAAAAGCAACAGATTCATTTGAAATTCTTAGGTAATCTTAACTGGGTATCACACCTATCATCCCAGGACTCCAGACTGAGGCAGGAGGATTGCTACAAGTTTGAGTCTAGTGTTAACTGAATAATGAGTTATGGCAGACTGGGATATAGTGTCTCAAAGTGTATCTGGGAGCCTGGGAGGCTGTGTCTCAAACAAACCCAGTGAAACAGGCTCAGTGGTAGAGGGTCCTGAGTCCCATTCTCAAGGTGGGAGAGAAGAATGCAATCTTTGCAATCTCCGTTTCTTGTCAGCATGGGTATCAGCAAGCATTGTGTCCTGTTAGTTCTTGCTTTCAGTCCCTCAAGCTGTCTATTGACAGGAGAGTAATTGTTTAATAGATTTGAGGGTAAAAGAAAGAGGGTATGGATTTACTTTAGATATAAGAATAACACAGCCGGGCGTGGTGGCACACGCCTTTAATCCCAGCACTTGGGAGGCAGAGGCAGGAAGATTTCTGAGTTTGAGGCCAGCCTGGTCTACAGTCTACACAGTGAGTTCTAGGACAGCCAGGGCTACACAGAGAAACCCTGTCTCAAAAAACCAAAACGAAAAAAAGGAAGAAAAAAGCAGTAGAAGTGCCAGGAAGGCTCCTGTGTGTGACCTCTCTCTTTTTGGAAGGTTAATTAATTTTTTGAGATTCAGTCTCATGTAGCTCAGCCTGGCCTTGAACTTGTTTGTAACTGAATTAGCATTGAACTGATTCTCCTTGCCTCTGCCTCCCACATGTCAAGGCTTCAGCCCTGTGCCACCACACCTGACAACATGTGTGGGATCTGGATGGTTGGCCCTTTCTGGTGAGCCTGGGGTCCTCTTGCCTGGAGGTGACCCTGCCTTCTTATGTCCCCAG
Seq C2 exon
AACAACCCTCCCGGTGTGCTGGCCCTGCTGGATGAAGAATGCTGGTTCCCCAAAGCTACAGACAAGTCTTTTGTGGAGAAGCTATGCTCAGAGCAGGGAAATCACCCCAAATTTCAGAAGCCCAAGCAGCTAAAGGACAAAACAGAGTTCTCCATCATCCACTATGCTGGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000018830:ENSMUST00000090287:13
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.069
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(8.3=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(8.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAACTCCTTCGAGCAGCTGTG
R:
CTTCCCAGCATAGTGGATGAT
Band lengths:
346-2004
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types